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Proteomicsto screen the Treg inhibitor and investigate its mechanism in tumor
No Treg-specific therapeutics has been approved for clinical use. Our project aim to screen the Treg inhibitor and investigate its mechanism in tumor.
ORGANISM(S): Homo sapiens (Human) 
2025-01-15 | PXD059236 | Pride
Human ip-ms runx1 
UnknownAssociation Between Disease Activity of Systemic Lupus Erythematosus and Resting Electrocardiogram Abnormalities.
Not available
S-EPMC11943163 | biostudies-literature
MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
TranscriptomicsMicroarray skeletal muscle miR-499 overexpressing mice
This experiment was conducted to identify target genes of the microRNA-499 in skeletal muscle of transgenic mice that overexpressed miR-499. The following abstract from the submitted manuscript describes the major findings of this work. Coupling of mitochondrial function and skeletal muscle f...
ORGANISM(S): Mus musculus 
2016-09-03 | E-GEOD-72581 | biostudies-arrayexpress
UnknownZ-Guggulsterone Induces Cell Cycle Arrest and Apoptosis by Targeting the p53/CCNB1/PLK1 Pathway in Triple-Negative Breast Cancer.
Not available
S-EPMC9851028 | biostudies-literature
UnknownViral Diversity and Epidemiology in Critically Endangered Yangtze Finless Porpoises (Neophocaena asiaeorientalis asiaeorientalis).
Not available
S-EPMC10434060 | biostudies-literature
Proteomicslnc-EAPV binding proteins in C57BL/6J BMDMs
Endogenous retroviruses (ERVs) are transposable elements that cause host genome instability and usually play deleterious roles such as tumorigenesis. Recent advances also suggest that this 'enemy within' may encode viral mimic to induce antiviral immune responses through viral sensors. Here, through...
ORGANISM(S): Mus musculus (Mouse) 
2018-11-07 | PXD011577 | Pride
Lnc-epav rbp bmdms 
MetabolomicsMulti-omics association analysis reveals interactions between the oropharyngeal microbiome and the metabolome in pediatric patients with influenza A virus pneumonia.
Children are at high risk for influenza A virus (IAV) infections, which can develop into severe illnesses. However, little is known about interactions between the microbiome and respiratory tract metabolites and their impact on the development of IAV pneumonia in children. Using a combination of liq...
2024-09-25 | MTBLS4816 | MetaboLights
ProteomicsDetection of Eepd1 myristoylation in vivo by data-independent acquisition mass spectrometry (DIA-MS)
Eight 8-week-old male C57BL/6J mice were injected with adenovirus expressing Eepd1-Flag (3×10^8/mouse) into multiple sites in their iWAT. Three days later, each mouse was administered 50 mg/kg of myristic acid solution (prepared in 0.1% BSA) via oral gavage. Half of the mice were then exposed to 8°C...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-23 | PXD058559 | Pride
Iwat Mouse Dia-ms Myristoylation Eepd1 
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
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