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The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear. Here, we demonstrated that a strain affiliated with Lactobacillus plantarum (de...
2024-01-16 | MTBLS4262 | MetaboLights
Primary human monocytes were isolated and differentiated into moDCs. These moDCs were infected with WT Dengue virus 2 and its attenuated mutants (generated using infectious clone construction with site-directed mutagenesis) to better understand the gene expression changes induced by these different ...
ORGANISM(S): Homo sapiens 
Halomonas species are renowned for their production of organic compatible solutes, particularly ectoine. However, the identification of key regulatory genes governing ectoine production in Halomonas remains limited. In this study, we conducted a combined transcriptome-proteome analysis to unveil add...
ORGANISM(S): Halomonas 
2024-11-02 | PXD057477 |
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | GNPS
We identified 1836 Class I (locnalization probabilities > 0.75) lactylated sites in 487 proteis,This study establish the first lactylome database in Caenorhabditis elegans and provides a basis for studying the role of lactylation. In addition, it provides a evidence for the existence of lactylation ...
ORGANISM(S): Caenorhabditis Elegans 
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