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TranscriptomicsTranscription profiling of mouse follicular and marginal zone B-cells
Immature B cells in spleens of mouse and human differentiate into at least two subsets of mature B cells, the follicular (FO) B cells and the marginal zone (MZ) B cells, but functions, maturation and other properties of these cells are largely unknown. To solve these questions, in this study, we per...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3599 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of primary cutaneous large B-cell lymphomas
High-throughput sequencing of primary cutaneous follicle center lymphoma (PCFCL), primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL-LT) and in vitro activated peripheral blood B-cells. We performed high-throughput sequencing analysis on frozen tumor biopsies from 19 cases of PCFCL an...
ORGANISM(S): Homo sapiens 
2013-10-18 | E-GEOD-51359 | biostudies-arrayexpress
TranscriptomicsCharacterization of expression changes in qin by tiling array
Qin, a novel protein comprising amino-terminal E3 ligase and five carboxy terminal Tudor domains, silences transposons and ensures genome stability in the Drosophila germline by promoting antisene piRNA amplification via Aubergine:Ago3 Ping-Pong and preventing futile Aubergine:Aubergine interactions...
ORGANISM(S): Drosophila melanogaster 
2011-11-18 | E-GEOD-30061 | biostudies-arrayexpress
GenomicsGenetic and Functional Drivers of Diffuse Large B Cell Lymphoma
Diffuse large B cell lymphoma (DLBCL) is the most common hematologic malignancy and is characterized by a striking degree of heterogeneity. We enrolled a total of 1001 DLBCL patients and comprehensively defined the landscape of genetic mutations, copy number alterations and expression through whole-...
EGAS00001002606 | EGA
TranscriptomicsPreactivation of the interferon signaling in liver is correlated with non-response to interferon alpha therapy in patients chronically infected with hepatitis B virus
To screen the differentially expressed genes between responders(Rs) and nonresponders(NRs) in CHB patients treated with IFN-α, and to explore the molecular basis for treatment failure.Expression profiling was performed on percutaneous needle liver biopsy specimens taken before therapy.Gene expressio...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-27555 | biostudies-arrayexpress
TranscriptomicsGeneration of clinical grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of B-cell malignancies
Long-lived, self-renewing, multipotent T memory stem cells (TSCM) can trigger profound and sustained tumor regression but their rareness poses a major hurdle to their clinical application. Presently, clinically compliant procedures to generate relevant numbers of this T cell population are undefined...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-68003 | biostudies-arrayexpress
TranscriptomicsTrivalent Inactivated Influenza Vaccine (TIV) and Live Attenuated Influenza Vaccine (LAIV) Induce Different B cell and Transcriptional Responses in Children
LAIV and TIV are effective for prevention of influenza infection in children, but the mechanisms associated with protection are still not well defined. We analyzed the differences in B cell responses and transcriptional profiles. Compared to baseline, LAIV elicited a significant increase in naM-CM-/...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-52005 | biostudies-arrayexpress
ProteomicsEarly cardiomyopathy in prediabetic NDPK-B-deficient mice is associated with remodeling of the mitochondrial O-GlcNAc proteome
Diabetic cardiomyopathy (DCM) is characterized by myocardial remodeling that may already be evident during prediabetes, yet the molecular alterations accompanying these early changes remain poorly understood. The present study examined mouse models of Nucleoside diphosphate kinase (NDPK-B)-deficient...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-21 | PXD081812 | Pride
Prediabetes  diabetes  ndpk-b  hbp  diabetic cardiomyopathy  mitochondria 
UnknownQin Huang formula enhances the effect of Adriamycin in B-cell lymphoma via increasing tumor infiltrating lymphocytes by targeting toll-like receptor signaling pathway.
Not available
S-EPMC9272877 | biostudies-literature
TranscriptomicsEffect of TGF-B treatment on human vascular smooth muscle cells
The authors did a microarray analysis to investigate the effect of TGF-B treatment on cultured smooth muscle cells from the human aorta. In particular, the authors were interested to see which cell types were upregulated or downregulated after treatment with TGF-B. Human Smooth muscle cells from 4 d...
ORGANISM(S): Homo sapiens 
2011-06-16 | E-GEOD-30004 | biostudies-arrayexpress
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