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GenomicsDNA methylation analysis of prostate cancer cell lines and tissues using Next Generation Sequencing
Beginning with precursor lesions, aberrant DNA methylation marks the entire spectrum of prostate cancer progression. We mapped the global DNA methylation patterns in prostate tissues (n=17) and cells (n=2) from fifty nanograms of genomic DNA using Methylplex-Next Generation Sequencing (M-NGS). A...
ORGANISM(S): Homo sapiens 
2011-05-09 | E-GEOD-27618 | biostudies-arrayexpress
TranscriptomicsGenome-wide copy number variation in Chinese schizophrenia trios
To reveal the risk CNVs of SZ in Chinese population, we recrited and enrolled 100 Chinese family trios with a schizophrenia affected children and both of their father and mother. SZ was diagnosed according to DSM-IV criteria by two independent psychiatrists. There gDNA we screen the genome-wide CNV...
ORGANISM(S): Homo sapiens 
2021-10-01 | E-MTAB-8075 | biostudies-arrayexpress
MetabolomicsMetabolomic profiling of Campylobacter jejuni with resistance gene ermB by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry and tandem quadrupole mass spectrometry
The metabolome changes of Campylobacter jejuni with resistant gene ermB remain unclear. Here, we described an untargeted metabolomic workflow based on ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry to investigate the metabolites perturbations mediated by erm...
2018-08-07 | MTBLS496 | MetaboLights
UnknownComparison of Ultrasound Guided and Conventional Techniques for Peripheral Venous Catheter Insertion in Pediatric Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Not available
S-EPMC8859100 | biostudies-literature
TranscriptomicsmRNA Sequencing of STG in schizophrenia
The RNA was extracted from post-mortem cortical grey matter of STG from the left hemisphere of 9 pairs of male subjects with schizophrenia and matched non-psychiatric controls. Each sample was subjected to 76 cycles of sequencing from a single end in one lane of Illumina Genome Analyzer II.
ORGANISM(S): Homo sapiens 
2013-03-08 | E-MTAB-1030 | biostudies-arrayexpress
TranscriptomicsGenomic analysis of xCT-mediated regulatory network: identification of novel targets against AIDS-associated lymphoma
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the etiological agent of primary effusion lymphoma (PEL), a rapidly progressing malignancy mostly arising in HIV-infected patients. Even under conventional chemotherapy, PEL continues to portend nearly 100% mortality within several months, which ur...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-65418 | biostudies-arrayexpress
UnknownCaspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial Cells.
Not available
S-EPMC4867131 | biostudies-literature
UnknownLipid metabolism of apoptotic vesicles accelerates cutaneous wound healing by modulating macrophage function.
Not available
S-EPMC11823102 | biostudies-literature
UnknownInhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration.
Not available
S-EPMC5503703 | biostudies-literature
UnknownOverexpression of HMGA1 confers radioresistance by transactivating RAD51 in cholangiocarcinoma.
Not available
S-EPMC8556338 | biostudies-literature
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