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MetabolomicsTranscriptomic and metabolomic data of Populus deltoides ‘Shalinyang’ (PdS) response to feeding of Anoplophora glabripennis adults
Populus deltoides ‘Shalinyang’ (PdS), a vital species for artificial shelterbelts in the arid regions of northwest China, has shown resistance to the destructive stem-boring beetle Anoplophora glabripennis Motschulsky (Asian longhorned beetle, ALB). However, comprehensive research in this area is st...
2026-03-25 | MTBLS12296 | MetaboLights
MetabolomicsEnterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance
Commensal intestinal bacteria play key roles in regulating cells mediating immune tolerance; however, bacterial strains and related metabolites directly involved in this regulation are largely unknown. Here, using a mouse model of dextran sulfate sodium (DSS)-induced colitis combined with different ...
2024-08-05 | MTBLS5585 | MetaboLights
ProteomicsProteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its vital importance in the biogenesis of glycosylphosphatidylinositol-anchored proteins
The SEL1L-HRD1 protein complex of endoplasmic reticulum (ER)-associated degradation (ERAD) plays indispensable roles for many physiological processes in a substrate-specific manner; however, the nature of endogenous substrates remains largely elusive. Here we have developed a unique proteomics strat...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-12-17 | PXD041803 | Pride
Endogenous substrates Pigk Disease mutants   Sel1l-hrd1 erad Proteomic screens Gpi-anchored proteins 
GenomicsReduced representation bisulfite sequencing data of mouse genome
RRBS was used to analyse global imprinting gene methylation pattern of offspring from the in vitro derived spermatids like cells and normal control Global imprinting gene methylation pattern comparision of two offspring (one male and one female) from the in vitro derived spermatids like cells and tw...
ORGANISM(S): Mus musculus 
2016-02-26 | E-GEOD-76238 | biostudies-arrayexpress
ProteomicsProteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its vital importance in the biogenesis of glycosylphosphatidylinositol-anchored proteins
The SEL1L-HRD1 protein complex of endoplasmic reticulum (ER)-associated degradation (ERAD) plays indispensable roles for many physiological processes in a substrate-specific manner; however, the nature of endogenous substrates remains largely elusive. Here we have developed a unique proteomics strat...
ORGANISM(S): Homo sapiens (Human) 
2023-12-17 | PXD041882 | Pride
Disease mutants Endogenous substrates Pigk Sel1l-hrd1 erad Proteomic screens Gpi-anchored proteins 
UnknownCLDN6 triggers NRF2-mediated ferroptosis through recruiting DLG1/PBK complex in breast cancer.
Not available
S-EPMC11845765 | biostudies-literature
UnknownCLDN6 inhibits breast cancer growth and metastasis through SREBP1-mediated RAS palmitoylation.
Not available
S-EPMC11337767 | biostudies-literature
UnknownCLDN6 induces chemoresistance through protective autophagy in breast cancer.
Not available
S-EPMC12435484 | biostudies-literature
UnknownCLDN6 Suppresses c-MYC-Mediated Aerobic Glycolysis to Inhibit Proliferation by TAZ in Breast Cancer.
Not available
S-EPMC8745066 | biostudies-literature
UnknownCLDN6 inhibits breast cancer metastasis through WIP-dependent actin cytoskeleton-mediated autophagy.
Not available
S-EPMC10026481 | biostudies-literature
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