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GenomicsCharacterization of TCF21 downstream target regions identifies a transcriptional network linking multiple independent coronary artery disease loci
Recent meta-analyses of genome wide association studies (GWAS) have identified approximately 150 loci that are associated with coronary artery disease (CAD). To link the causal genes in these loci to functional transcriptional networks, we have used chromatin immunoprecipitation sequencing (ChIP-Seq...
ORGANISM(S): Homo sapiens 
2015-04-12 | E-GEOD-61369 | biostudies-arrayexpress
TranscriptomicsA long noncoding RNA protects the heart from pathological hypertrophy
The role of long noncoding RNA (lncRNA) in adult hearts is unknown; also unclear is how lncRNA modulates nucleosome remodelling. An estimated 70% of mouse genes undergo antisense transcription1, including myosin heavy chain 7 (Myh7), which encodes molecular motor proteins for heart contraction2. Her...
ORGANISM(S): Homo sapiens 
2014-08-05 | E-GEOD-49716 | biostudies-arrayexpress
UnknownThe Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Not available
S-EPMC10231654 | biostudies-literature
UnknownPopulation-scale tissue transcriptomics maps long non-coding RNAs to complex disease.
Not available
S-EPMC8651477 | biostudies-literature
UnknownIdentification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
Not available
S-EPMC3696959 | biostudies-literature
UnknownInterleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.
Not available
S-EPMC3316940 | biostudies-literature
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