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TranscriptomicsMouse Gpr88
Gpr88 is an orphan G protein-coupled receptor highly expressed in the striatum, a region important for motor control and learning. We developed a mouse lacking this receptor (genotype Gpr88Cre/Cre) by replacing most of the open-reading-frame of the Gpr88 gene with Cre recombinase. When comparing th...
ORGANISM(S): Mus musculus 
2012-10-15 | E-MTAB-1282 | biostudies-arrayexpress
ProteomicsMitochondrial Proteome of Affected Neurons in a Mouse Model of Leigh Syndrome
Defects in mitochondrial function lead to severe neuromuscular orphan pathologies known as mitochondrial disease. Among them, Leigh Syndrome is the most common pediatric presentation, characterized by symmetrical brain lesions, hypotonia, motor and respiratory deficits, and premature death. Mitochon...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-28 | PXD016321 | Pride
Proteomics Cell type-specific Animal models Neuroscience Leigh syndrome Mitochondrial isolation 
UnknownImmunohistochemical diagnosis of human infectious diseases: a review.
Not available
S-EPMC8801197 | biostudies-literature
UnknownDistinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.
Not available
S-EPMC5776984 | biostudies-literature
UnknownDeconvolution of the Response to Bacillus Calmette-Guerin Reveals NF-κB-Induced Cytokines As Autocrine Mediators of Innate Immunity.
Not available
S-EPMC5507989 | biostudies-literature
UnknownGenetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations.
Not available
S-EPMC5075285 | biostudies-literature
UnknownFundamental Anatomy and its Impact on Clinical Practice: The Membranous Septum and Conduction System in TAVI.
Not available
S-EPMC12789789 | biostudies-literature
UnknownComplex hybridization patterns in European pond turtles (Emys orbicularis) in the Pyrenean Region.
Not available
S-EPMC6206128 | biostudies-literature
UnknownThe immune factors driving DNA methylation variation in human blood.
Not available
S-EPMC9537159 | biostudies-literature
TranscriptomicsStandardized whole-blood transcriptional profiling enables the deconvolution of complex induced immune responses
The study employs a standardized whole-blood stimulation systems to test the hypothesis that responses to Toll-like receptor ligands or whole microbes can be defined by the combined transcriptional signatures of key effector cytokines. The study encompasses the analysis of 21 distinct whole blood st...
ORGANISM(S): Homo sapiens 
2016-08-04 | E-GEOD-85176 | biostudies-arrayexpress
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