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GenomicsRegulation of autophagy by Rab27B in colorectal cancer
Regulation of autophagy by Rab27B in colorectal cancer
PRJNA1114032 | ENA
TranscriptomicsRegulation of autophagy by Rab27B in colorectal cancer
Autophagy is a cellular recycling process that can promote tumor growth, anti-tumor immune response, and resistance to therapy in colorectal cancer (CRC). Here, we show that small GTPase Rab27B, a known regulator of vesicle trafficking and extracellular vesicle secretion, to control the autophagy pr...
ORGANISM(S): Homo sapiens 
2025-05-10 | GSE268007 | GEO
ProteomicsTGF-β regulates the release of breast cancer cell-derived extracellular vesicles and the sorting of their protein cargo by downregulating RAB27B expression
Extracellular vesicles (EVs) are important mediators of intercellular communications in tumor microenvironment (TME). EV-mediated TGF-β signaling in the TME facilitates tumor metastasis and immune evasion by transferring TGF-β ligands and regulators to recipient cells. The mechanisms of how TGF-β af...
ORGANISM(S): Homo sapiens (Human) 
2024-12-28 | PXD052799 | Pride
Extracellular vesicles Tgf-β Rab27b 
UnknownRAB27B requirement for stretch-induced exocytosis in bladder umbrella cells.
Not available
S-EPMC6335015 | biostudies-literature
UnknownRAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.
Not available
S-EPMC10266782 | biostudies-literature
GenomicsHomo sapiens
RAB27B in renal cell carcinoma
PRJDB9372 | ENA
UnknownRab27b contributes to radioresistance and exerts a paracrine effect via epiregulin in glioblastoma.
Not available
S-EPMC7770522 | biostudies-literature
UnknownThe GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein.
Not available
S-EPMC7278354 | biostudies-literature
UnknownEffect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis.
Not available
S-EPMC2886092 | biostudies-literature
UnknownRab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland.
Not available
S-EPMC3154548 | biostudies-literature
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