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ProteomicsTitin BioID - protein and peptide pull-down
Proximity proteomics has greatly advanced the analysis of native protein complexes and subcellular structures in culture, but has not been amenable to study development and disease in vivo. Here, we generated a knock-in mouse with the biotin ligase (BioID) inserted at titin’s Z-disc region to identi...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-18 | PXD017341 | Pride
Mouse Titin Biotinylation sites Bioid 
TranscriptomicsCoordinated Progression Through Two Subtranscriptomes Underlies the Tachyzoite Cycle of Toxoplasma gondii
We describe the cell cycle transcriptome of the Toxoplasma gondii that has emerged as a major genetic model for the study of Apicomplexa parasites. Two distinct transcriptional waves accompany the relatively simple binary replication of tachyzoite stage (endodyogeny) functionally separating conserv...
ORGANISM(S): Toxoplasma gondii 
2010-08-27 | E-GEOD-19092 | biostudies-arrayexpress
TranscriptomicsGenome-wide copy number analysis of patient-derived gliobastoma cell cultures
Genome-wide copy number variation profiles were analyzed in the patient-derived gliobastoma cell culture samples. For this purpose, gDNA was analyzed using the CytoScan® assay in combination with a one-color based labeling and hybridization protocol. Signals on the CytoScan® HD microarrays were dete...
ORGANISM(S): Homo sapiens 
2019-02-28 | E-MTAB-7649 | biostudies-arrayexpress
TranscriptomicsLaser Capture Microdissection of Hyperlipidemic Mouse Aorta Atherosclerosis
Atherosclerosis is a transmural chronic inflammatory condition of small and large arteries that is associated with adaptive immune responses at all disease stages. However, impacts of adaptive immune reactions on clinically apparent atherosclerosis such as intima lesion (plaque) rupture, thrombosis,...
ORGANISM(S): Mus musculus 
2011-11-03 | E-GEOD-21419 | biostudies-arrayexpress
TranscriptomicsWhole blood expression profiling from a general population (KORA F4)
The development of whole genome association studies from the general population has lead to the robust identification of several loci involved in different common human diseases. Interestingly, most of the strongest signals of association observed in these studies arise from non-coding regions, rais...
ORGANISM(S): Homo sapiens 
2013-07-13 | E-MTAB-1708 | biostudies-arrayexpress
UnknownIschemic Events Occur Early in Patients Undergoing Percutaneous Coronary Intervention and Are Reduced With Cangrelor: Findings From CHAMPION PHOENIX.
Not available
S-EPMC8765214 | biostudies-literature
UnknownEfficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.
Not available
S-EPMC5731244 | biostudies-literature
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