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ProteomicsTargeting non-canonical NF-κB signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha
Proteome of CD45- sorted healthy skin (C1-C5) and CD45-/CD200+ CYLD cutaneous syndrome tumour samples (T1-T5).
ORGANISM(S): Homo sapiens (Human) 
2026-05-13 | PXD053466 | Pride
Cyld Skin Human Nf-kb 
ProteomicsEffect of insulin receptor knockdown on the proteome and secretome of CYLD cutaneous syndrome primary keratinocytes
CYLD cutaneous syndrome (CCS) is a rare genetic disorder characterized by multiple skin appendage tumors. This study investigated the impact of insulin receptor (INSR) knockdown on the cellular proteome and secretome of CCS primary keratinocytes. Three biological replicates each of control and INSR ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-28 | PXD071326 | Pride
Keratinocytes insr cyld 
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