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Human skeletal tissue contains an abundance of proteins some of which may be preserved over geological timescales. The profiling of proteins from ancient individuals — or palaeoproteomics —has begun to provide new information about the diseases suffered in past societies. We describe here the first ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-20 | PXD008479 | Pride
We describe the first dental proteomic profiles of Iron Age individuals (c2000-1000 years B.P), collected from the site of Long Long Rak rock shelter (LLR) in northwest Thailand. A bias toward the preservation of small, acidic and hydrophobic amino acids is observed. It is evident that the 212 prote...
ORGANISM(S): Homo sapiens (Human) 
2019-02-25 | PXD009418 | Pride
Visfatin (VIS) is a hormone belonging to the adipokines’ group secreted mainly by the adipose tissue. VIS plays a crucial role in the control of energy homeostasis, inflammation, cell differentiation, and angiogenesis. VIS expression was confirmed in the hypothalamic-pituitary-gonadal (HPG) axis str...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-07-03 | PXD047445 | Pride
Granulosa cells (Gc) in the ovary play a vital role in nurturing oocyte development, producing estrogens, and maintaining the hormonal balance necessary for follicle maturation and successful ovulation. Omentin-1 (ITLN1) is an adipokine involved in energy metabolism and insulin resistance; its expre...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2025-07-23 | PXD061976 | Pride
To investigate the role of the transcription factor ERG in hematopoiesis we generated Erg heterozygous knockout and conditional Erg knockout mice. We found that several hematopoietic cell types were decreased in these mice. To define Erg downstream target genes in hematopoietic stem cells, we sorted...
ORGANISM(S): Mus musculus 
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