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GenomicsRnmt and Ram regulate the activated CD4 T cell transcriptome
Rnmt and Ram regulate the activated CD4 T cell transcriptome
PRJNA815845 | ENA
TranscriptomicsRnmt and Ram regulate the activated CD4 T cell transcriptome
We investigated the role of RNMT and its cofactor RAM in T cells using conditional knockout mouse models. We demonstrate that RNMT and RAM have broadly overlapping roles in CD4 T cell activation.
ORGANISM(S): Mus musculus 
2024-04-08 | GSE198541 | GEO
TranscriptomicsmRNA cap methylation in pluripotency and differentiation
The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating subunit, RAM, is elevated in ESCs resulting i...
ORGANISM(S): Mus musculus 
2016-06-14 | E-GEOD-81849 | biostudies-arrayexpress
ProteomicsCryopreservation and egg yolk medium alter the proteome of ram spermatozoa
Cryopreservation causes significant lethal and sub-lethal damage to spermatozoa. In order to improve freezing outcomes, a comprehensive understanding of sub-lethal damage is required. Cryopreservation induced changes to sperm proteins have been investigated in several species, but few have employed ...
ORGANISM(S): Ovis aries 
2018-04-26 | PXD009331 | Pride
Swath Sperm Ram 
UnknownRAM is upregulated during T cell activation and is required for RNA cap formation and gene expression.
Not available
S-EPMC10989996 | biostudies-literature
UnknownEffects of Linker Length and Transient Secondary Structure Elements in the Intrinsically Disordered Notch RAM Region on Notch Signaling.
Not available
S-EPMC5576018 | biostudies-literature
UnknownTargeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8+ T cells in the tumor microenvironment.
Not available
S-EPMC6186121 | biostudies-literature
ProteomicsExtending the Mass Spectrometry-Detectable Landscape of the Immunopeptidome by use of Restricted access Material
Mass spectrometry-based immunopeptidomics enables the comprehensive identification of major histocompatibility complex (MHC) peptides from cell culture as well as from tissue or tumor samples and is increasingly applied for the identification of tumor-specific and viral T-cell epitopes. Although mas...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-11-07 | PXD034017 | Pride
Immunopeptidomics Solid phase extraction Restricted access material 
UnknownThermodynamic analysis of the CSL x Notch interaction: distribution of binding energy of the Notch RAM region to the CSL beta-trefoil domain and the mode of competition with the viral transactivator EBNA2.
Not available
S-EPMC2825463 | biostudies-literature
ProteomicsProteomic characterization and comparison of spermatozoa proteomes between ram (Ovis. aries) and buck (Capra. hircus) using a data-independent acquisition-mass spectrometry (DIA-MS)
Artificial insemination in small ruminants is most commonly performed using fresh semen due to the low fertility rates typically achieved with frozen spermatozoa. Usually, when developing and applying assisted reproductive technologies, sheep and goats are often lumped together as one specie. In ord...
ORGANISM(S): Ovis aries Capra hircus (Goat) 
2020-05-26 | PXD014095 | Pride
Proteomics Spermatozoa protein Buck Data-independent acquisition Ram 
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