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The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating subunit, RAM, is elevated in ESCs resulting i...
ORGANISM(S): Mus musculus 
Ram kund, Jharkhand Metagenomic assembly
Seminal plasma proteome of ram and impact on semen liquid preservation.
ORGANISM(S): Ovis aries 
2014-08-18 | PXD000822 | Pride
Cryopreservation causes significant lethal and sub-lethal damage to spermatozoa. In order to improve freezing outcomes, a comprehensive understanding of sub-lethal damage is required. Cryopreservation induced changes to sperm proteins have been investigated in several species, but few have employed ...
ORGANISM(S): Ovis aries 
2018-04-26 | PXD009331 | Pride
Rnmt and Ram regulate the activated CD4 T cell transcriptome
Enterobacter hormaechei strain:RAM MAlQtan7980 Genome sequencing
mRNA cap addition occurs early during RNA pol II transcription, facilitating pre-mRNA processing and translation. We report that the mammalian mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription, independently of mRNA capping and translation. In cells, sub-lethal suppression of R...
ORGANISM(S): Homo sapiens 
2018-05-01 | GSE87767 | GEO
We investigated the role of RNMT and its cofactor RAM in T cells using conditional knockout mouse models. We demonstrate that RNMT and RAM have broadly overlapping roles in CD4 T cell activation.
ORGANISM(S): Mus musculus 
2024-04-08 | GSE198541 | GEO
Artificial insemination in small ruminants is most commonly performed using fresh semen due to the low fertility rates typically achieved with frozen spermatozoa. Usually, when developing and applying assisted reproductive technologies, sheep and goats are often lumped together as one specie. In ord...
ORGANISM(S): Ovis aries Capra hircus (Goat) 
2020-05-26 | PXD014095 | Pride
Long non-coding RNAs are important regulators of diverse biological prosesses. Here, we report on functional identification and characterization of a novel long intergenic noncoding RNA with MyoD-regulated and skeletal muscle-restricted expression that promotes the activation of the myogenic program...
ORGANISM(S): Mus musculus 
2016-12-25 | GSE72601 | GEO
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