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UnknownAKT Inhibition Promotes Nonautonomous Cancer Cell Survival.
Not available
S-EPMC4707053 | biostudies-literature
TranscriptomicsAsymmetric cancer cell division regulated by AKT, Reactive Oxygen Species (ROS) high versus ROS low mRNA
Human tumors often contain slowly proliferating cancer cells that resist treatment but we do not know precisely how these cells arise. We show that rapidly proliferating cancer cells can divide asymmetrically to produce slowly proliferating “G0-like” progeny that are enriched following chemotherapy ...
ORGANISM(S): Homo sapiens 
2011-07-14 | E-GEOD-30465 | biostudies-arrayexpress
UnknownDownregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas.
Not available
S-EPMC6448261 | biostudies-literature
TranscriptomicsFra1 silencing in MDA-MB-231 cells
Fra1 silencing in MDA-MB-231 cells
ORGANISM(S): Homo sapiens 
2013-07-24 | E-MTAB-1230 | biostudies-arrayexpress
TranscriptomicsmicroRNA Profiling in Wilms Tumors and Kidney Tissues
The IGF2-intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis. The expression levels of microRNAs were profiled in 20 human Wilms tumor samples (WT), 3 human normal adult kidney samples (AK) and 5 human fetal kidney samples (FK) using a Luminex bea...
ORGANISM(S): Homo sapiens 
2013-12-22 | E-GEOD-50505 | biostudies-arrayexpress
TranscriptomicsExpression data from zinc-finger-transcription-factor-induced Fulvestrant-Resistant MCF7 Cell Lines
Multiple gene expression studies have demonstrated that breast cancer biological diversity is associated with distinct transcriptional programs. Transcription factors, because of their unique ability to coordinate the expression of multiple genes, are speculated to play a role in generating phenotyp...
ORGANISM(S): Homo sapiens 
2011-07-17 | E-GEOD-27444 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MCF-7 cells treated with Fulvestrant (ICI 182,780) and vehicle reveals origins and phenotypic variations of antiestrogen resistance in breast cancer
Expression profiles of MCF-7 cells treated with Fulvestrant (ICI 182,780) and vehicle Experiment Overall Design: MCF7 cells were grown in DMEM supplemented with 5% FCS (Hyclone, "Defined" grade). Growth medium was changed immediately before addition of 100 nM of ICI 182,780 or vehicle alone (0.1% et...
ORGANISM(S): Homo sapiens 
2009-09-15 | E-GEOD-14986 | biostudies-arrayexpress
GenomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [ChIP-Seq]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42477 | biostudies-arrayexpress
TranscriptomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [miRNA profiling]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42475 | biostudies-arrayexpress
TranscriptomicsDefining a molecular roadmap of cellular reprogramming into iPS cells [mRNA profiling]
Factor induced reprogramming is a slow and inefficient process with only rare cells progressing towards induced pluripotent stem cells (iPSCs). Owing to these restraints, mechanistic studies have been limited to analyses of heterogeneous bulk populations undergoing reprogramming and partially reprog...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-42379 | biostudies-arrayexpress
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