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Detailed characterization of complex biological surfaces by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) requires instrumentation that is capable of high mass resolving power, mass accuracy and dynamic range. Fourier transform ion cyclotron resonance mass sp...

2022-01-28 | MTBLS3154 | MetaboLights
This study investigates the function of the C-terminal GT1 domain of chloroplast RNase J in Arabidopsis thaliana, focusing on its role in RNA quality control and double-stranded RNA (dsRNA) metabolism. To characterize the molecular effects of GT1 domain disruption, comparative proteomic analyses wer...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-01-18 | PXD069635 | Pride
Microarrays were used to determine the transcriptional profile of Y. pestis that is growing inside macrophages. J774A.1 macrophage-like cells were infected with Y. pestis KIM5 and incubated in the presence of gentamicin in tissue culture media. RNA was isolated from intracellular bacteria at vari...
ORGANISM(S): Yersinia pestis 
RNA sequencing of A431 cell line samples before and after gefitinib treatment, at 0, 2, 6 and 24 hours, was performed in order to characterize the cell line's early and late response to this drug, and to compare against proteomics (mass spectrometry) characterization of the cell line using the same ...
ORGANISM(S): Homo sapiens 
Array Comparative Genomic Hybridization (aCGH) is a widely used technique to assess chromosomal copy number alterations. Chromosomal content, however, is often not uniform throughout cell populations. The aim of our present study is to evaluate to what extent aCGH can detect DNA copy number alterat...
ORGANISM(S): Homo sapiens 
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