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ProteomicsProteomic analysis of S-acylated proteins in human retinal pigment epithelial cells reveals the role of palmitoylation of Niemann–Pick type C1 protein in cholesterol transportation
Palmitoylation is a dynamic process which regulates the activity of the modified proteins. Retinal pigment epithelial (RPE) cells play pivotal roles in visual cycle and maintaining healthy photoreceptor cells. Dysfunctional RPE cells are often associated with degenerative retinal diseases. The aim o...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD034896 | Pride
Niemann-pick type c1 protein Retinal pigment epithelial cells Palmitoylation 
UnknownMultiple strategies were adopted to optimize the enzymatic characteristics and improve the expression of bovine chymosin BtChy in <i>Kluyveromyces lactis</i> for cheese production.
Not available
S-EPMC12158995 | biostudies-literature
ProteomicsHuman lung cancer cells-MS for SNHG3 c.1746A>I editing
Adenosine-to-inosine (A-to-I) RNA editing is a critical post-transcriptional modification that enhances tumor genome diversity and contributes to cancer progression. In non-small cell lung cancer (NSCLC), while specific A-to-I editing events have been identified, their functional mechanisms and clin...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD067139 | Pride
Human Lung Snhg3 
ProteomicsAlanine and glutamate catabolism collaborate to ensure the success of sporulation in Bacillus subtilis
Sporulation as a typical bacterial differentiation process has been studied for decades. However, two crucial aspects of sporulation, (i) the energy sources supporting the process, and (ii) the maintenance of spore dormancy throughout sporulation, are scarcely explored. Here, we reported the crucial...
ORGANISM(S): Bacillus Subtilis Py79 
PXD052983 |
TranscriptomicsEmbryonic stem cell study
Cell culture: H9 hESCs were grown using feeder-free conditions for 7 days after passage then either RNA was harvested or embryoid bodies were prepared, cultured in suspension for 4 days, plated on gelatin-coated plates, and cultured for an additional 9 days in embryoid body medium. Detailed protocol...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-1310 | biostudies-arrayexpress
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS pos assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS286 | MetaboLights
MetabolomicsIdentification of Conserved and Diverse Metabolic Shifts during Rice Grain Development (LC-MS neg assay)

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS287 | MetaboLights
UnknownDNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.
Not available
S-EPMC4957136 | biostudies-literature
UnknownLignin valorization to bioplastics with an aromatic hub metabolite-based autoregulation system.
Not available
S-EPMC11519575 | biostudies-literature
UnknownOsthole Attenuates Macrophage Activation in Experimental Asthma by Inhibitingthe NF-ĸB/MIF Signaling Pathway.
Not available
S-EPMC8020258 | biostudies-literature
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