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TranscriptomicsComprehensive gene expression profile of human livers from patients with biliary atresia at the time of diagnosis and the corresponding disease and normal controls
Liver biopsy samples were obtained from 64 infants with biliary atresia at the time of intraoperative cholangiogram. Liver biopsy samples were obtained from 14 age-matched infants with other causes of intrahepatic cholestasis, and from 7 deceased-donor children. GeneChip® Human Gene 1.0 ST Array (Af...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-46960 | biostudies-arrayexpress
TranscriptomicsStaging of biliary atresia at diagnosis by molecular profiling of the liver
BACKGROUND: Young age at portoenterostomy has been linked to improved outcome in biliary atresia, but pre-existing biological factors may influence the rate of disease progression. In this study, we aimed to determine whether molecular profiling of the liver identifies stages of disease at diagnosis...
ORGANISM(S): Homo sapiens 
2010-08-31 | E-GEOD-15235 | biostudies-arrayexpress
TranscriptomicsComprehensive gene expression profile of extrahepatic bile ducts in mice with experimental biliary atresia
Newborn Balb/c mice were injected intraperitoneally with 1.5x10^6 fluorescent-forming units (ffu) of type- A Rhesus Rotavirus (RRV) or 0.9% normal saline (NS; control) within 24 hours of birth to induce experimental model of biliary atresia. Extrahepatic bile ducts including gallbladder were microdi...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-46967 | biostudies-arrayexpress
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