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Proteomics(AP-MS) Kinase Suppressor of RAS 1 (KSR1) maintains the transformed phenotype of BRAFV600E mutant human melanoma cells
KSR1 is a scaffolding protein for the RAS-RAF-MEK-ERK pathway, which is one of the most frequently altered pathways in human cancers. Previous results have shown that KSR1 has a critical role in mutant RAS mediated transformation. Here, we examined the role of KSR1 in mutant BRAF transformation. We ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD036261 | Pride
Ksr1 Ras_raf-mek-erk pathway Melanoma Apoptosis Proliferation Senescence 
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