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TranscriptomicsCharacterization of the RNA content of chromatin
We deep sequenced chromatin-associated RNAs (CARs) from human fibroblast (HF) cells. This resulted in the identification of 141 intronic regions and 74 intergenic regions harbouring CARS. We purified CARs from normal HFs by isolating soluble chromatin after MNase treatment, followed by separation of...
ORGANISM(S): Homo sapiens 
2010-04-13 | E-GEOD-21227 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for Chronic Lymphocytic Leukemia_diagnostic sample_patient samples
High-resolution genomic microarrays provides simultaneous detection of copy-number aberrations such as the known recurrent aberrations in Chronic Lymphocytic Leukemia_diagnostic sample_patient (del(11q), del(13q), del(17p) and trisomy 12), and copy-number neutral loss of heterozygosity. We screened...
ORGANISM(S): Homo sapiens 
2011-04-28 | E-GEOD-28030 | biostudies-arrayexpress
TranscriptomicsSNP array analysis of lung cancer NCI-H1395, diluted to different tumor cell concentrations
In vitro mix of DNA from patient-matched lung cancer and blood cell lines, representing 30,50,70,100% tumor cell tissue, analyzed on Affymetrix 6.0 arrays. Lung cancer cell line H-1395 and patient-matched blood cell line BL1395 were obtained from ATCC and cultured according to their recommendations....
ORGANISM(S): Homo sapiens 
2011-09-08 | E-GEOD-29172 | biostudies-arrayexpress
TranscriptomicsAllele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity
Chromosomal aberrations were studied both in a lung cancer cell line and colorectal cancer tumor samples. Results were verified by SKY karyotypes and by DNA ploidy analysis. The sensitivity of detecting chromosomal aberrations in tumor samples was evaluated by analyzing data from simulated mixtures ...
ORGANISM(S): Homo sapiens 
2011-09-08 | E-GEOD-26302 | biostudies-arrayexpress
UnknownCardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis.
Not available
S-EPMC4648058 | biostudies-literature
UnknownVariability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway.
Not available
S-EPMC4337973 | biostudies-literature
UnknownPopulation-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.
Not available
S-EPMC8863274 | biostudies-literature
UnknownA polygenic resilience score moderates the genetic risk for schizophrenia.
Not available
S-EPMC7058518 | biostudies-literature
UnknownGenomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.
Not available
S-EPMC6432650 | biostudies-literature
UnknownComplement genes contribute sex-biased vulnerability in diverse disorders.
Not available
S-EPMC7319891 | biostudies-literature
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