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ProteomicsRauvolfia tetraphylla latex proteome
Monoterpene indole alkaloids (MIAs) are a structurally diverse family of specialized metabolites mainly produced in Gentianales to cope with environmental challenges. Due to their pharmacological properties, the biosynthetic modalities of several MIA types have been elucidated but not that of the yo...
ORGANISM(S): Rauvolfia tetraphylla 
2024-01-26 | PXD046315 | Pride
Yohimbane Medium chain dehydrogenase/reductase Rauwolscine Yohimbine Alkaloid Geissoschizine 
UnknownDexmedetomidine-Induced Aortic Contraction Involves Transactivation of the Epidermal Growth Factor Receptor in Rats.
Not available
S-EPMC9024600 | biostudies-literature
UnknownDihydroergotamine inhibits the vasodepressor sensory CGRPergic outflow by prejunctional activation of α2-adrenoceptors and 5-HT1 receptors.
Not available
S-EPMC5970131 | biostudies-literature
UnknownThe second extracellular loop of alpha2A-adrenoceptors contributes to the binding of yohimbine analogues.
Not available
S-EPMC2189838 | biostudies-literature
TranscriptomicsA zebrafish model of NEXMIF-related encephalopathy identified drivers of hyperlocomotion and provides a scalable platform for drug discovery
X-linked Intellectual Disability type 98 (XLID-98) is a neurodevelopmental disorder (NDD) with a broad phenotypic spectrum caused by pathogenic variants in the Neurite Extension and Migration Factor (NEXMIF) gene, formerly known as KIAA2022, KIDLIA or XPN (OMIM 300524). To investigate the pathogenic...
ORGANISM(S): Danio rerio 
2026-08-19 | GSE334219 | GEO
UnknownIdentification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors.
Not available
S-EPMC3000660 | biostudies-literature
UnknownA Concise, Enantioselective Approach for the Synthesis of Yohimbine Alkaloids.
Not available
S-EPMC7185878 | biostudies-literature
UnknownThe Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids.
Not available
S-EPMC10673892 | biostudies-literature
UnknownIdentification of Potential Poly (ADP-Ribose) Polymerase-1 Inhibitors Derived from Rauwolfia serpentina: Possible Implication in Cancer Therapy.
Not available
S-EPMC8967534 | biostudies-literature
UnknownElucidating Antiangiogenic Potential of Rauwolfia serpentina: VEGFR-2 Targeting-Based Molecular Docking Study.
Not available
S-EPMC8860507 | biostudies-literature
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