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Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein rbm14
Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development
RNA-binding proteins with intrinsically disordered regions (IDRs) such as Rbm14 can phase separate in vitro. To what extent the phase separation contributes to their physiological functions is however unclear. Here we show that zebrafish rbm14 regulates embryonic dorsoventral patterning through phas...
ORGANISM(S): Danio rerio 
2019-08-05 | GSE128984 | GEO
Early embryonic development depends on proper utilization and clearance of maternal transcriptomes. How these processes are spatiotemporally regulated remains unclear. Here we show that nuclear RNA-binding protein Rbm14 and maternal mRNAs co-phase separate into cytoplasmic condensates to facilitate ...
ORGANISM(S): Danio rerio Mus 
2022-12-03 | GSE179035 | GEO
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