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RNA binding motif protein 42 (RBM42) is an understudied gene mapped to 19q13.12 region and codes for a protein that consists of 480 amino acids, containing one RNA recognition motif (RRM) at its C-terminal region. We mapped the RBM42 interactome using ascorbate peroxidase (APEX2)-based proximity lab...
ORGANISM(S): Homo sapiens (Human) 
2023-11-22 | PXD034854 | Pride
Here we are using unbiased proteomic analysis based on affinity purification and MS to try to identify specific interactors of RBM42 in Panc-1 human PDAC cells.
ORGANISM(S): Homo sapiens (Human) 
2025-01-13 | PXD058353 | Pride
To explore the role of RBM42 in the DNA damage response, we sought to determine the transcriptome of RBM42-proficient and -deficient cells following DNA damage induction. RNA samples were prepared from etoposide (VP16) treated HCT116 cells transfected with control or RBM42 siRNA, and subjected RNA-s...
ORGANISM(S): Homo sapiens 
RNA-seq of RBM42-proficient and -deficient HCT116 cell line after VP16 treatment
A dual role of RBM42 in modulating splicing and translation of CDKN1A/p21 during DNA damage response
This study compares the transcriptomic changes induced by RBM42 knockdown in human SH-SY5Y cells. Two biological replicates of cells transduced with an letivirus-mediated shRNA against RBM42 (shRBM42_1) and two replicates of cells transduced with a non-targeting control shRNA (shRBM42_NC) were subje...
ORGANISM(S): Homo sapiens 
2026-10-07 | GSE311526 | GEO
To identify RNAs bound by RBM42 in SH-SY5Y cells, RNA immunoprecipitation followed by sequencing (RIP-seq) was performed. Anti-RBM42 antibody was used for immunoprecipitation, with IgG as the negative control. Total RNA input samples were also sequenced. Three biological replicates were included for...
ORGANISM(S): Homo sapiens 
2026-10-07 | GSE311642 | GEO
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