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ProteomicsStress-Specific Carbonylation and Proteasome 20S Activity in Potato under Drought, Elevated Temperature, and Combined Stresses: Linking Oxidative Damage to Proteome Regulation
This study investigates stress-specific patterns of protein carbonylation and proteome re-modelling in potato leaves subjected to drought, elevated temperature, and their combina-tion. The research was conducted at the Department of Potato Agronomy of the Plant Breeding and Acclimatization Institute...
ORGANISM(S): Solanum tuberosum (Potato) 
2026-04-06 | PXD075691 | Pride
Drought stress Solanum tuberosum l. Protein carbonylation Elevated temperature 
UnknownOne-Year Survival after Cardiac Surgery in Frail Older People-Social Support Matters: A Prospective Cohort Study.
Not available
S-EPMC10381118 | biostudies-literature
GenomicsPatterns and mechanisms of ancestral histone protein inheritance in budding yeast
It is widely believed that chromatin, the nucleoprotein packaging state of eukaryotic genomes, can carry epigenetic information to propagate gene expression patterns in replicating cells. However, inheritance of genomic packaging status is subject to mechanistic challenges that do not confront the i...
ORGANISM(S): Saccharomyces cerevisiae 
2011-10-06 | E-GEOD-28269 | biostudies-arrayexpress
MetabolomicsStable isotope resolved analysis of HUVEC Cells under normaxia and hypoxia
In order to analyze HUVECs under normoxia and hypoxia, cells were initially deprived of excess nutrients and hormones by maintaining them overnight in a restricted medium with only 2% fetal bovine serum, and incubated for 40 hours in the presence of the tracer [1,2-13C2]-glucose until sample collect...
2017-12-18 | MTBLS412 | MetaboLights
TranscriptomicsA Key Role for Chd1 in Histone H3 Dynamics at the 3' Ends of Long Genes in Yeast (gene expression)
Chd proteins are ATP-dependent chromatin remodeling enzymes implicated in biological functions from transcriptional elongation to control of pluripotency. Here, we examine roles of Chd1 in replication- independent dynamics of histone H3 in yeast. Using genome-wide ChIP on chip analysis, we find tha...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-07 | E-GEOD-38496 | biostudies-arrayexpress
UnknownDisease activity 4.5 years after starting cladribine: experience in 264 patients with multiple sclerosis.
Not available
S-EPMC10638874 | biostudies-literature
GenomicsDynamic Changes in Ezh2 Gene Occupancy Underlie Its Involvement in Neural Stem Cell Self-Renewal and Differentiation towards Oligodendrocytes
BACKGROUND: The polycomb group protein Ezh2 is an epigenetic repressor of transcription originally found to prevent untimely differentiation of pluripotent embryonic stem cells. We previously demonstrated that Ezh2 is also expressed in multipotent neural stem cells (NSCs). We showed that Ezh2 expres...
ORGANISM(S): Mus musculus 
2012-07-30 | E-GEOD-31655 | biostudies-arrayexpress
ProteomicsInvestigation of DNA double-strand break repair mechanisms in microsatellite regions using the CRISPR/Cas9 system
Expansion of the CAG/CTG repeats in functionally unrelated genes is a causative factor in many inherited neurodegenerative disorders, including Huntington's disease (HD), spinocerebellar ataxias (SCAs) and myotonic dystrophy type 1 (DM1). Despite many years of research, the mechanism responsible for...
ORGANISM(S): Homo sapiens (Human) 
2024-11-04 | PXD044960 | Pride
Trinucleotide repeats Genome editing Huntington disease Dna repair Rispr-cas 
UnknownMulti-institutional study of post-transplantation cyclophosphamide as single-agent graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation using myeloablative busulfan and fludarabine conditioning.
Not available
S-EPMC4209101 | biostudies-literature
MetabolomicsComparative metabolomics analysis of bronchial epithelium during barrier establishment after allergen exposure

BACKGROUND: Several studies have shown a correlation between an altered metabolome and respiratory allergies. The epithelial barrier hypothesis proposes that an epithelial barrier dysfunction can result in allergic diseases development. Der p 1 allergen from house dust mite is a...

2023-08-22 | MTBLS1755 | MetaboLights
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