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MetabolomicsA noteworthy response process of Microcystis aeruginosa induced by exogenous reactive oxygen species in algae-laden water treatment
The effectiveness of reactive oxygen species (ROS) generated by advanced oxidation processes (AOPs) in inactivating harmful algae in drinking water varies considerably. Therefore, the physiological and biochemical reactions of algae need to be considered to clarify the underlying mechanisms. Herein,...
2024-09-26 | MTBLS8024 | MetaboLights
MetabolomicsGlucose potentiates florfenicol killing of antibiotic-resistant V. parahaemolyticus by enhancing proton motive force and reactive oxygen species

 Florfenicol is valued for its clinical safety, particularly its reduced bone marrow toxicity compared to other old antibiotics of chloramphenicols. However, the rise of bacterial resistance threatens its efficacy. To address this, we evolved a florfenicol-resistant strain of Vibrio par...

2025-10-14 | MTBLS13132 | MetaboLights
MetabolomicsSertraline Hydrochloride Exposure Leads to Reactive Oxygen Species Burst in Model Microalgae Species (Raphidocelis subcapitata)

Microalgae play important ecological roles and serve as useful models for assessing impacts of environmental contaminants on lower trophic aquatic organisms. Sertraline, a commonly prescribed selective serotonin reuptake inhibitor (SSRI) found in urban waters, has been observed to induce chlorosi...

2025-08-18 | MTBLS12869 | MetaboLights
MetabolomicsReactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Inflammatory bowel disease is characterized by chronic relapsing idiopathic inflammation of the gastrointestinal tract and persistent inflammation. Studies focusing on the immune-regulatory function of reactive oxygen species (ROS) are still largely missing. In this study, we analyzed an ROS-deficie...
2019-05-22 | MTBLS593 | MetaboLights
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7711 | MetaboLights
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7713 | MetaboLights
TranscriptomicsTranscription profiling by array of Burkholderia cenocepacia J2315 was exposed to heat stress and to stress form reactive oxygen species
B. cenocepacia J2315 was exposed to heat stress and to stress form reactive oxygen species.
To expose the cultures to heat stress, cells were grown at 37ºC to an O.D. of 0.4 to 0.45 and then transferred into a different shaking incubator at 42.5ºC, incubated for 1 hour at 150 rpm and harvested.<...
ORGANISM(S): Burkholderia cenocepacia 
2012-01-01 | E-MEXP-2791 | biostudies-arrayexpress
TranscriptomicsHigh REDOX RESONSIVE TRANSCRIPTION FACTOR1 levels result in accumulation of reactive oxygen species in Arabidopsis thaliana shoots and roots [mature leaves]
Redox Responsive Transcription Factor1 (RRTF1) in Arabidopsis is rapidly and transiently upregulated by H202, as well as biotic and abiotic induced redox signals. Inactivation of RRTF1 restricts and overexpression promotes reactive oxygen species (ROS) accumulation in response to stress. Overexpress...
ORGANISM(S): Arabidopsis thaliana 
2015-04-23 | E-GEOD-64853 | biostudies-arrayexpress
ProteomicsOxygen-confined photooxidation represents a novel form of oxidative protein damage
Oxidative modifications can disrupt protein folds and functions, and are strongly associated with human aging and diseases. Conventional oxidation pathways typically involve the free diffusion of reactive oxygen species (ROS), which primarily attack the protein surface. Yet, it remains unclear wheth...
ORGANISM(S): Homo Sapiens (human) Escherichia Coli 
2024-11-27 | PXD056895 | JPOST Repository
TranscriptomicsSINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii
To identify components involved in the signal transduction and activation of the singlet oxygen-mediated response, a mutant selection was performed. This led to the isolation of the singlet oxygen resistant 1 (sor1) mutant, which is more tolerant to singlet oxygen-producing chemicals and shows a con...
ORGANISM(S): Chlamydomonas reinhardtii 
2012-04-03 | E-GEOD-33548 | biostudies-arrayexpress
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