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TranscriptomicsNucleotide-resolution, genome-wide transcriptome maps of Propionibacterium acnes (cultured with and without potassium downshift)
This data contained within this entry was produced as part of a study that included differential RNA-sequencing and microarray analysis. The results of the latter two have also been deposited in GEO Duplicate cultures of Propionibacterium acnes strain KPA171202 were grown exponentially in Holland S...
ORGANISM(S): Propionibacterium acnes KPA171202 
2013-05-15 | E-GEOD-46883 | biostudies-arrayexpress
TranscriptomicsNucleotide-resolution, genome-wide, 5'-end maps of the transcriptome of Propionibacterium acnes (cultured with and without potassium downshift)
The differential RNA-seq data contained within this entry is complemented by global RNA-seq and microarray data, which is also deposited in GEO. Duplicate cultures of Propionibacterium acnes strain KPA171202 were grown exponentially in batch culture under anaerobic growth. Samples were taken followi...
ORGANISM(S): Propionibacterium acnes KPA171202 
2013-05-10 | E-GEOD-46810 | biostudies-arrayexpress
ProteomicsDistinct protein signature of hypertension-induced damage in the renal proteome of the two-kidney, one-clip ratmodel
Background: Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-02-28 | PXD012889 | Pride
Hypertension 2k1c Juxtamedullary cortex Kidney 
TranscriptomicsMicroarray analysis of Merkel cell carcinoma (MCC) tumors, small cell lung cancer (SCLC) tumors, and MCC cell lines
When using cell lines to study cancer, phenotypic similarity to the original tumor is paramount. Yet, little has been done to characterize how closely Merkel cell carcinoma (MCC) cell lines model native tumors. To determine their similarity to MCC tumor samples, we characterized MCC cell lines via g...
ORGANISM(S): Homo sapiens 
2014-12-23 | E-GEOD-50451 | biostudies-arrayexpress
TranscriptomicsComparison of nucleotide-resolution, genome-wide transcriptome maps of Escherichia coli K12 strain BW25113 and Streptomyces coelicolor A3(2) strain M145.
This data contained within this entry was produced as part of a study that included differential RNA-sequencing. S. coelicolor and E. coli reference strains were grown in batch culture with shaking. The E. coli sample was extracted during mid-exponential growth, while the S. coelicolor sample was ex...
ORGANISM(S): Escherichia coli K-12 
2013-04-20 | E-GEOD-46232 | biostudies-arrayexpress
TranscriptomicsSIRT6 suppresses pancreatic cancer through control of Lin28b
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-04-01 | E-GEOD-79505 | biostudies-arrayexpress
GenomicsGenome-wide maps of EGR2 transcription factor binding sites in T cell anergy
We report the application of sequencing technology for mapping the EGR2 transcriptional program in T cell anergy Examination of Egr2 genomic binding sites in T cells following overnight treatment with immobilized anti-CD3 mAb (1ug/ml)
ORGANISM(S): Mus musculus 
2013-04-21 | E-GEOD-46241 | biostudies-arrayexpress
TranscriptomicsTranscriptome of the demosponge Amphimedon queenslandica at life cycle transitions
Poriferans, like the demosponge Amphimedon queenslandica, are the earliest diverging metazoans and may hold the key to understanding the evolution of metazoan pathways. A. queenslandica exhibits a biphasic lifecycle, with free-swimming larvae and sessile adult stages. To study changes in the transcr...
ORGANISM(S): Amphimedon queenslandica 
2012-07-10 | E-GEOD-29978 | biostudies-arrayexpress
TranscriptomicsDifferential adipose tissue gene expression profiles in abacavir treated patients that may contribute to cardiovascular risk: a microarray study
Objective: to compare changes in gene expression by microarray from subcutaneous adipose tissue from HIV treatment naïve patients treated with efavirenz based regimens containing abacavir (ABC), tenofavir (TDF) or zidovidine (AZT). There were significant divergence between ABC and the other two grou...
ORGANISM(S): Homo sapiens 
2015-04-16 | E-GEOD-62117 | biostudies-arrayexpress
TranscriptomicsComparison of the nucleotide-resolution, genome-wide, 5'-end maps of the transcriptomes of Escherichia coli K12 strain BW25113 and Streptomyces coelicolor A3(2) strain M145
The differential RNA-seq data contained within this entry is complemented by global RNA-seq. S. coelicolor and E. coli reference strains were grown in batch culture with shaking. The E. coli sample was extracted during mid-exponential growth, while the S. coelicolor sample was extracted at the start...
ORGANISM(S): Escherichia coli BW25113 
2013-05-01 | E-GEOD-46507 | biostudies-arrayexpress
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