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ProteomicsProteomic and functional analysis identifies proteins related to embryonic development in decidua of patients with early recurrent miscarriage
Recurrent miscarriage (RM) is the occurrence of repeated pregnancies that end in miscarriage of the fetus before 20 weeks of gestation. Recurrent miscarriages affect about 1-2% of couples trying to conceive; however, mechanisms leading to this complication are largely unknown. Our previous studies u...
ORGANISM(S): Homo sapiens (Human) 
2021-07-30 | PXD023849 | Pride
Recurrent miscarriage  tmt  decidua  ipa  embryonic development 
TranscriptomicsGenotyping by array of affected sib-pairs with recurrent miscarriage
siblings of patients with idiopathic recurrent miscarriage have a higher risk of miscarriage.
We hypothesized that this in part was conferred by shared genetic factors.
We took blood samples from patients with three or more miscarriages and from siblings with two or more miscarriages in order...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-MEXP-2942 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling of placental villi from karyotypically normal recurrent miscarriage
Miscarriage occurs in 15-20% of clinical pregnancies. While chromosomal errors are observed in over 50%, causes of karyotypically normal losses are poorly understood. DNA methylation undergoes reprogramming during development and must be appropriately set to maintain a healthy pregnancy. We hypothes...
ORGANISM(S): Homo sapiens 
2016-07-04 | E-GEOD-43256 | biostudies-arrayexpress
GenomicsDNA methylation profiling in recurrent miscarriage
DNA methylation profiling in recurrent miscarriage
PRJNA593016 | ENA
GenomicsCharacteristic DNA methylation profiles of chorionic villi in recurrent miscarriage
Characteristic DNA methylation profiles of chorionic villi in recurrent miscarriage
PRJNA816500 | ENA
TranscriptomicsThe YY1/MMP2 axis promotes trophoblast invasion at the maternal-fetal interface
YY1 is a sequence-specific DNA-binding transcription factor that has many important biological roles. However, its function in trophoblasts at the maternal-foetal interface remains to be elucidated. In this study, we used an mRNA microarray and quantitative reverse transcription-PCR and compared the...
ORGANISM(S): Homo sapiens 
2016-01-21 | E-GEOD-76862 | biostudies-arrayexpress
GenomicsEndometrial microbiota in women with recurrent miscarriage, recurrent implantation failure and a control group who had had live birth
Endometrial microbiota in women with recurrent miscarriage, recurrent implantation failure and a control group who had had live birth
PRJNA544596 | ENA
Methylation profilingDNA methylation profiling in recurrent miscarriage
We used the Illumina Infinium HumanMethylation450 array platform to conduct a genome-wide screening of DNA methylation in decidua samples from the products of conception of women with recurrent miscarriage and to identify novel methylation variable positions (MVPs) and differentially methylated regi...
ORGANISM(S): Homo sapiens 
2019-12-03 | GSE141298 | GEO
GenomicsExploring the mechanism of Shoutai wan's intervention in recurrent miscarriage based on transcriptomics
Exploring the mechanism of Shoutai wan's intervention in recurrent miscarriage based on transcriptomics
PRJNA869686 | ENA
Methylation profilingCharacteristic DNA methylation profiles of chorionic villi in recurrent miscarriage
Genome wide DNA methylation profiling of chorionic villi and decidua from recurrent miscarriage patients and artificial abortion controls. Infinium HumanMethylation450 BeadChip was used.
ORGANISM(S): Homo sapiens 
2022-04-24 | GSE198700 | GEO
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