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ProteomicsSEC23B-dependent COPII Vesicles Regulate T Cell Immunity
The coordinated release of proteins by T cells enables controlled biological responses. While the molecular mechanisms underlying T cell secretion are being increasingly understood, whether the critical ER-to-Golgi trafficking pathway regulates T cell immunity is not known. We utilized mice with a T...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD015766 | Pride
Lc-msms Lymphocytes Mouse 
UnknownMulticenter, randomized controlled trial of yoga for sleep quality among cancer survivors.
Not available
S-EPMC3757292 | biostudies-literature
GenomicsGenome-wide Binding of Acetylated-STAT3 Demonstrates Negative Regulation of Dendritic Cells
Dendritic cells (DC) play a vital role in the induction of activation or tolerance of immune response. STAT3 is a master transcriptional regulator of immune response in DCs by positively or negatively regulating DC function, but the mechanisms are unknown. STAT3 is post-translationally modified by ...
ORGANISM(S): Mus musculus 
2015-11-05 | E-GEOD-74262 | biostudies-arrayexpress
TranscriptomicsExpression data from B6 mouse miR-142 KO and WT T cells
T cells are critical for modulating immune responses. miRNAs are small, noncoding RNAs and play a significant role in T cell responses. miR-142 is a hematopoietic specific miRNA. To explore the potential role of miR-142 in regulating T cell responses, we generated mutant mice bearing a targeted de...
ORGANISM(S): Mus musculus 
2014-05-13 | E-GEOD-57543 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse T cells after CLIP (Crosslinking immunoprecipitation) procedures (mRNA)
Molecular networks based on genome-wide mRNA and miRNA expression in activated T cells are interated by co-regulation with miRNA and protein-coding genes during immune responses, however, accurate prediction of miRs and their targets remains a challenge. Furthermore, the specific changes in the expr...
ORGANISM(S): Mus musculus 
2013-01-19 | E-GEOD-43635 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse T cells after CLIP (Crosslinking immunoprecipitation) procedures (microRNA)
Molecular networks based on genome-wide mRNA and miRNA expression in activated T cells are integrated by co-regulation with miRNA and protein-coding genes during immune responses, however, accurate prediction of miRs and their targets remains a challenge. Furthermore, the specific changes in the exp...
ORGANISM(S): Mus musculus 
2013-01-19 | E-GEOD-43634 | biostudies-arrayexpress
UnknownBach2 repression mediates Th17 cell induced inflammation and associates with clinical features of advanced disease in chronic pancreatitis.
Not available
S-EPMC5833222 | biostudies-literature
TranscriptomicsMouse Dendritic Cells Expression Data
Dendritic cells (DC) play a vital role in the induction of activation or tolerance of immune response. Histone deacetylase (HDAC) inhibitors potently modulate experimental graft-vs-host disease, allograft rejection, and autoimmune diseases, partly through the regulation of dendritic cells. The mole...
ORGANISM(S): Mus musculus 
2015-10-24 | E-GEOD-74306 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse dendritic cells
Dendritic cells (DCs) are pivotal for both recognition of antigens and control of an array of immune responses by recognizing microbes through distinct pattern recognition receptors (PRRs). The first microbial component to be studied in detail and known to cause septic shock is endotoxin (LPS). DCs...
ORGANISM(S): Mus musculus 
2011-04-05 | E-GEOD-28340 | biostudies-arrayexpress
TranscriptomicsComparison of naïve, postmitotic (CD44-lo/CD62L-hi) and effector (CD44-hi/CD62L-lo) CD8+ Tcells during BMT in GVHD mice
Naïve CD44-lo/CD62L-hi/CD8+ T cells from C3H.SW mice were compared to CD44-hi/CD82L-lo/CD8+ effector memory T cells and CD44-lo/CD62L-hi/CD8+ postmitotic T cells, using 3 biological replicates of each type of sample. The later two cells types were highly purified at day 14 after transplantation fr...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-13743 | biostudies-arrayexpress
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