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MetabolomicsRedox proteomics reveal a role for peroxiredoxinylation in stress protection.

The redox state of proteins is essential for their function and guarantees cell fitness. Peroxiredoxins protect cells against oxidative stress, maintain redox homeostasis, act as chaperones, and transmit hydrogen peroxide signals to redox regulators. Despite the profound structural and functional...

2025-07-17 | MTBLS11979 | MetaboLights
MetabolomicsApplication of the redox metabolite detection method for profiling redox state following pharmacologic perturbation with methotrexate
Not available
ORGANISM(S): Homo sapiens 
ST001764 | MetabolomicsWorkbench
MetabolomicsApplication of the redox metabolite detection method for profiling redox state following pharmacologic perturbations of redox balance in cells (part III)
Not available
ORGANISM(S): Homo sapiens 
ST001771 | MetabolomicsWorkbench
MetabolomicsApplication of the redox metabolite detection method for profiling redox state following pharmacologic perturbations of redox balance in cells (part II)
Not available
ORGANISM(S): Homo sapiens 
ST001770 | MetabolomicsWorkbench
MetabolomicsApplication of the redox metabolite detection method for profiling redox state following pharmacologic perturbations of redox balance in cells (part I)
Not available
ORGANISM(S): Homo sapiens 
ST001769 | MetabolomicsWorkbench
ProteomicsMechano-redox control of Mac-1 de-adhesion from ICAM-1 by protein disulfide isomerase promotes directional movement under flow
Quantification of the redox state of disulfide bonds in the beta 2 subunit of human recombinant Mac-1 integrin.
ORGANISM(S): Homo sapiens (Human) 
2023-04-09 | PXD032688 | Pride
Mac-1 Disulfide bonds Redox state 
MetabolomicsMetabolomics Analysis Identifies Glutamic acid and Cystine imbalances in COVID-19 Patients Without Comorbid Conditions. Implications on Redox Homeostasis and COVID-19 Pathophysiology

It is well known that the presence of comorbidities and age-related health issues may hide biochemical and metabolic features triggered by SARS-CoV-2 infection and other diseases associated to hypoxia, as they are by themselves chronic inflammatory conditions that may potentially disturb metaboli...

2024-08-26 | MTBLS5011 | MetaboLights
ProteomicsAnalysis of cysteine redox state with age in flies overexpressing catalase
Dysregulation of redox homeostasis has been implicated in the ageing process and the pathology of age-related diseases. To study redox signalling by hydrogen peroxide in vivo, we upregulated levels of the enzyme catalase in Drosophila.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-06-30 | PXD060330 | Pride
Drosophila Catalase Ageing 
ProteomicsRedox-state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis
In an endotoxaemic mouse model of sepsis, a tissue-based proteomics approach for biomarker discovery identified long pentraxin 3 (PTX3) as the lead candidate for inflamed myocardium. PTX3 accumulated as an octamer due to disulphide-bond formation in heart, kidney and lung ?common organ dysfunctions ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-11-10 | MSV000081708 | MassIVE
TranscriptomicsClostridium thermocellum DSM 1313 Transcriptional Responses to Redox Perturbation
Clostridium thermocellum is a promising CBP candidate organism capable of directly converting lignocellulosic biomass to ethanol. Low yields, productivities and growth inhibition prevent industrial deployment of this organism for commodity fuel production. Symptoms of potential redox imbalance suc...
ORGANISM(S): Ruminiclostridium thermocellum DSM 1313 
2015-07-29 | E-GEOD-71465 | biostudies-arrayexpress
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