Redox-signaling

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CHEBI ID

CHEBI:17234 (9)
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Metabolite Name

Creatine (7)
Cytosine (6)
Betaine (6)
Taurine (6)
AMP (6)
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GMP (4)
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Niacinamide (4)
Deoxyuridine (4)

First Public Date

2026 (74)
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2013 (1)

Modelling Approach

Ordinary differential equation model (6)
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Lab affiliation

CRUK Scotland Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (6)
Department of Inflammation and Immunity, Gastroenterology and Hepatology. Cleveland Clinic, Cleveland Ohio, USA (6)
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 USA (3)
University of Colorado Skaggs School of Pharmacy (2)
Segal Cancer Proteomics Centre,Lady Davis Institute, Jewish General Hospital (2)
Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia (2)
Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia. (2)
WWU Muenster, Institute of Plant Biology and Biotechnology (2)
Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States (2)
National Center for Protein Science Beijing (2)
College of Horticulture, Northwest A&F University (2)
Department of Plant Bioscience, Life and Industry Convergence Research Institute, Pusan National University, Miryang, 50463, Republic of Korea (2)
College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China (1)
State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China (1)
Pusan National University, South Korea (1)
University Hospital Bern (1)
Iowa State University - Department of Biochemistry Biophysics and Molecular Biology (1)
Department of Surgery Hollings Cancer Center (HO 512H) Medical University of South Carolina (1)
Center for Molecular Medicine, Molecular Cancer Research, University Medical Center Utrecht, Universiteitsweg 100, 3584CG, Utrecht, The Netherlands. (1)
National Center for Protein Sciences Beijing (1)
University of Newcastle, Callaghan, NSW, Australia (1)
Instituto de Tecnologia Química e Biológica. Lab of Proteomic of Non-model Organism (1)
Professor i molekylærbiologi og faglig leder av PROMEC Institutt for klinisk og molekylær medisin Fakultet for medisin og helsevitenskap geir.slupphaug@ntnu.no 72573076 91825455 Laboratoriesenteret, 231.05.034, Øya, Erling Skjalgssons g 1 (1)
University Medical Center Mainz, Germany, Institute for Immunology (1)
Organic Mass Spectrometry Laboratory, Department of Chemical Sciences, University of Catania, Via S. Sofia 64, 95123 Catania, Italy (1)
Department of Vascular Dysfunction, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Straße 7-11, 68167 Mannheim, Germany. Department of Vascular Dysfunction, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Straße 7-11, 68167 Mannheim, Germany. (1)
Centro Nacional de Biotecnología (CNB-CSIC), Darwin, 3, 28049 Madrid, Spain (1)
Center for Proteome Analysis, Indiana University School of Medicine, Indianapolis, IN (1)
College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China (1)
College of Bioscience and Biotechnology, Shenyang Agricultural University, Shenyang 110866, PR China (1)

IsPrivate

False (7)

Classification

bacteria (4)
fungi (1)

Modification

2x(15)N labeled L-lysine (2)
4x(15)N labeled L-arginine (2)
6-dioxaoctanediamine derivatized cysteine (1)

Study type

Transcription profiling by array (87)
RNA-seq of coding RNA (15)
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Release Date

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Divergent Cysteines in FOXO3 and FOXO4 Mediate Paralog-Specific Redox Signaling

Reduction-oxidation (redox) signaling, the translation of an oxidative intracellular environment into a cellular response, is mediated by the reversible oxidation of specific cysteine thiols. The latter results in disulfide formation between protein (hetero)dimers that alter protein function until t...

ORGANISM(S): Homo sapiens (Human)

2014-08-26 | PXD001041 | Pride

Foxo3 reduction-oxidation (redox) signaling

Peroxiredoxins and Redox Signaling in Plants.

Not available

S-EPMC5806080 | biostudies-literature

Evolutionary Acquisition of Cysteines determines FOXO Paralog-Specific Redox Signaling

Data from ProteomeXchange, PXD ID: PXD001018. Experiment: HRV_A, file: folder summary. Published as part of Antioxid Redox Signal. 2014 Jul 29 . From the Abstract: {{i}} Reduction-oxidation (redox) signaling, the translation of an oxidative intracellular environment into a cellular response, is med...

ORGANISM(S): Homo_sapiens_viruses, Human

GPM32320002469 | GPMDB

Resource Reanalysis

Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox Signaling.

Not available

S-EPMC6071544 | biostudies-literature

Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling.

Not available

S-EPMC4270166 | biostudies-literature

Novel redox-sensing modules: accessory protein- and nucleic acid-mediated signaling.

Not available

S-EPMC3277925 | biostudies-literature