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Obesity and related metabolic syndromes pose a growing global health challenge, increasingly linked to severe complications including cardiovascular disease, type 2 diabetes, and non-alcoholic fatty liver disease. High-fat diet (HFD) serves as a key environmental driver of obesity, disrupting gut...

2026-01-04 | MTBLS13595 | MetaboLights
Genome-wide analyses have identified thousands of long non-coding RNAs (lncRNAs). Malat1 (Metastasis Associated Lung Adenocarcinoma Transcript 1) is among the most abundant lncRNAs whose expression is altered in numerous cancers. Here we report that genomic loss, as well as systemic knockdown of Mal...
ORGANISM(S): Mus musculus 
Cysteine disulfide bridges can be reduced by chemical methods, like an incubation with DTT. However, reduction with an electrochemical method has also been demonstrated. Electrochemical reduction can be implemented online, after LC separation and before mass spectrometry. For the study of antibody m...
ORGANISM(S): Homo sapiens (Human) 
2022-05-27 | PXD021649 | Pride
sludge reduction Raw sequence reads
Analysis of a Bradyrhizobium japonicum pmtA mutant. PmtA catalyzes the first of three consecutive methylation reactions leading to phosphatidylcholine (PC) formation in B. japonicum. Disruption of the pmtA gene results in a significantly reduced PC content causing a defect in symbiosis with the soyb...
ORGANISM(S): Bradyrhizobium japonicum 
In this study, we systematically evaluated reduction and alkylation of proteins using three reducing agents (DTT, TCEP, and BME) in combination with four alkylation agents (IAA, IAC, AA, and CAA). We tested these conditions using strong anion exchange (SAX) fractionated in-solution digests and in-ge...
ORGANISM(S): Homo sapiens (Human) 
2017-05-30 | PXD005183 | Pride
G. lucidum could reduce selenite to element Se and further aggregated into selenium nanoparticles (SeNPs), simultaneously accompanying by the production of pungent odorous volatile selenium metabolites. iTRAQ-based quantitative proteomic analysis revealed the abundance of proteins involved in sele...
ORGANISM(S): Ganoderma Lucidum G.260125-1 
2022-08-03 | PXD035786 |
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