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Oral food intake maintains gastrointestinal cell turnover and impacts the morphology and function of intestinal epithelial cells. However, the underlying mechanism is not fully elucidated, especially in the large intestine. Therefore, we analyzed the colonic epithelial cell turnover in starved and r...
ORGANISM(S): Mus musculus 
Hepatic gene expression profiles during fed–fasted–refed state in mice [mRNA-seq]
Hepatic gene expression profiles during fed–fasted–refed state in mice [miRNA-seq]
Spatial landscapes of the fed, fasted and refed livers from C57BL/6J mice - spatial transcriptomics
Regulation of nutrient status during fasting and refeeding plays an important role in maintaining metabolic homeostasis in the liver. Thus, we investigated the impact of the physiological fed–fasted–refed cycle on hepatic gene expression in nutrient-sensitive mice. We performed transcriptomic analys...
ORGANISM(S): Mus musculus 
2023-02-24 | GSE225695 | GEO
Regulation of nutrient status during fasting and refeeding plays an important role in maintaining metabolic homeostasis in the liver. Thus, we investigated the impact of the physiological fed–fasted–refed cycle on hepatic gene expression in nutrient-sensitive mice. We performed transcriptomic analys...
ORGANISM(S): Mus musculus 
2023-02-24 | GSE225696 | GEO
Transcript data from liver receptor homolog-1 (LRH-1) WT and LRH-1 K289R livers from mice fasted for 24h followed by 6h refed. We used microarrays to detail the global program of gene expression underlying hepatic function under refed conditions.
ORGANISM(S): Mus musculus 
2017-01-19 | GSE89877 | GEO
Excessive glucose production in the liver is a key factor in the hyperglycemia observed in diabetes mellitus type 2. It is generally agreed to result from an increase in hepatic gluconeogenesis. Considerable attention has been devoted to the transcriptional regulation of key gluconeogenic enzymes, b...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-01 | PXD019755 | Pride
Spatial heterogeneity and plasticity of the mammalian liver is critical for systemic metabolic homeostasis in response to fluctuating nutritional status. Here, we generated a high-resolution transcriptomic landscape of the livers from mice that were either fed chow (fed), fasted for 18 h (fasted), o...
ORGANISM(S): Mus musculus 
2023-01-12 | GSE222796 | GEO
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