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ProteomicsQuantitative proteomics after spinal cord injury in a regenerative and a non-regenerative stage in Xenopus laevis
The capacity to regenerate the spinal cord after an injury is a coveted trait that only a limited group of non-mammalian organisms can achieve. In Xenopus laevis, this capacity is only present during larval or tadpole stages, but is absent during postmetamorphic frog stages. This provides an excelle...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2018-01-25 | PXD006993 | Pride
Spinal cord injury Regenerative and a non-regenerative stage Quantitative proteomics Xenopus laevis 
GenomicsCellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis.
Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis.
PRJNA689548 | ENA
TranscriptomicsCellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis.
Background: The efficient regenerative abilities at larvae stages followed by a non-regenerative response after metamorphosis in froglets makes Xenopus an ideal model organism to understand the cellular responses leading to spinal cord regeneration. Methods: We compared the cellular response to spin...
ORGANISM(S): Xenopus laevis 
2021-01-05 | GSE164204 | GEO
UnknownCellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis.
Not available
S-EPMC7852093 | biostudies-literature
UnknownGenome-wide expression profile of the response to spinal cord injury in Xenopus laevis reveals extensive differences between regenerative and non-regenerative stages.
Not available
S-EPMC4046850 | biostudies-literature
TranscriptomicsTranscription profiling of Xenopus hindlimbs during stage-dependent complete and incomplete regeneration
Xenopus laevis tadpoles are capable of limb regeneration following amputation, in a process which initially involves the formation of a blastema. However, Xenopus has full regenerative capacity only through premetamorphic stages. We have used the Affymetrix Xenopus laevis Genome Genechip® microarr...
ORGANISM(S): Xenopus laevis 
2008-06-13 | E-GEOD-4738 | biostudies-arrayexpress
UnknownTNFα Induces Muller Glia to Transition From Non-proliferative Gliosis to a Regenerative Response in Mutant Zebrafish Presenting Chronic Photoreceptor Degeneration.
Not available
S-EPMC6962764 | biostudies-literature
UnknownSpinal Cord Cells from Pre-metamorphic Stages Differentiate into Neurons and Promote Axon Growth and Regeneration after Transplantation into the Injured Spinal Cord of Non-regenerative Xenopus laevis Froglets.
Not available
S-EPMC5733487 | biostudies-literature
TranscriptomicsRestoration of anterior regeneration in a planarian with limited regenerative ability
Variability of regenerative potential among animals has long perplexed biologists. Based on their amazing regenerative abilities, planarians have become important models for understanding the molecular basis of regeneration; however, planarian species with limited regenerative abilities are also fou...
ORGANISM(S): Procotyla fluviatilis 
2013-07-04 | E-GEOD-48497 | biostudies-arrayexpress
TranscriptomicsRecurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and their Differentiated Derivatives [Illumina Infinium 450K DNA Methylation]
Human pluripotent stem cells (hPSCs) are potential sources of cells for modeling disease and development, drug discovery, and regenerative medicine. However, it is important to identify factors that may impact the utility of hPSCs for these applications. In an unbiased analysis of 205 hPSC and 130 s...
ORGANISM(S): Homo sapiens 
2012-05-13 | E-GEOD-31848 | biostudies-arrayexpress
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