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UnknownChronic Lymphocytic Leukemia (CLL)-Derived Extracellular Vesicles Educate Endothelial Cells to Become IL-6-Producing, CLL-Supportive Cells.
Not available
S-EPMC11273944 | biostudies-literature
GenomicsA unique regulatory phase of DNA methylation in the early mammalian embryo
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of global cytosine methylation at fertilization, followed by passive depletion that reaches a minimum at the blastocyst stage. However, this model is based on limit...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-34864 | biostudies-arrayexpress
TranscriptomicsStructure and Function of a Transcriptional Network Activated by Hog1
Cells regulate gene expression using a complex network of signaling pathways, transcription factors and promoters. To gain insight into the structure and function of these networks we analyzed gene expression in single and multiple mutant strains to build a quantitative model of the Hog1 MAPK-depen...
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-29 | E-GEOD-12270 | biostudies-arrayexpress
TranscriptomicsComprehensive comparative analysis of strand-specific RNA sequencing methods
Strand-specific massively-parallel cDNA sequencing (RNA-Seq) is a powerful tool for novel transcript discovery, genome annotation, and expression profiling. Despite multiple published methods for strand-specific RNA-Seq, no consensus exists as to how to choose between them. Here, we developed a co...
ORGANISM(S): Saccharomyces cerevisiae 
2010-08-15 | E-GEOD-21739 | biostudies-arrayexpress
Proteomics,MultiomicsDynamic profiling of the protein life cycle in response to pathogens
Jovanovic M,Rooney M, Mertins P, Przybylski D, Chevrier N, Satija R, Rodriguez EH, Fields AP, Schwartz S, Raychowdhury R, Mumbach M, Eisenhaure T, Rabani M, Gennert D, Lu D, Delorey T, Weissman JS, Carr SA, Hacohen N, Regev A, submitted 2015. Protein expression is regulated by production and degrada...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-01-15 | MSV000078994 | MassIVE
GenomicsSkin-resident innate lymphoid cells converge on a pathogenic effector state
Skin-resident innate lymphoid cells converge on a pathogenic effector state
PRJNA629379 | ENA
UnknownNew Insights on DR and DQ Human Leukocyte Antigens in Anti-LGI1 Encephalitis.
Not available
S-EPMC10042442 | biostudies-literature
ProteomicsA regression-based analysis of ribosome-profiling data reveals a conserved complexity to mammalian translation
Alexander P. Fields, Edwin H. Rodriguez, Marko Jovanovic, Noam Stern-Ginossar, Brian J. Haas, Philipp Mertins, Raktima Raychowdhury, Nir Hacohen, Steven A. Carr, Nicholas T. Ingolia, Aviv Regev, and Jonathan S. Weissman.Molecular Cell 2015. A fundamental goal of genomics is to identify the complete ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-10-30 | MSV000079361 | MassIVE
TranscriptomicsComprehensive comparative analysis of RNA sequencing methods for degraded or low input samples
RNA-Seq is an effective method to study the transcriptome, but can be difficult to apply to scarce or degraded RNA from fixed clinical samples, rare cell populations, or cadavers. Recent studies have proposed several methods for RNA-Seq of low quality and/or low quantity samples, but their relative ...
ORGANISM(S): Homo sapiens 
2013-05-15 | E-GEOD-40705 | biostudies-arrayexpress
GenomicsGenome-wide nucleosome position data for 12 yeast species
We mapped nucleosome positions genome-wide in 12 Ascomycetes Illumina sequencing of mononucleosomal DNA isolated from mid-log cultures grown in rich medium (abbreviated CM, in house recipe)
ORGANISM(S): Candida albicans 
2010-07-06 | E-GEOD-22211 | biostudies-arrayexpress
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