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ProteomicsImmunoprecipitation-proteomics analysis of MCPIP3/Regnase-3 interactors.
The monocyte chemotactic protein-induced protein 3 (MCPIP3), or Regnase-3, is a ribonuclease belonging to the MCPIP family. The aim of this study was to gain insights into the mechanisms by which MCPIP3 affects keratinocytes biology. Immunoprecipitation-proteomics was applied to identify putative in...
ORGANISM(S): Homo sapiens (Human) 
2025-09-28 | PXD067727 | Pride
Keratinocytes Proteomics Mcpip3 Regnase-3 
GenomicsEffect of loss of Regnase-1 and Regnase-3 on the transcriptional profile in mouse Lin–Sca1+Kit+ (LSK) cells
Effect of loss of Regnase-1 and Regnase-3 on the transcriptional profile in mouse Lin–Sca1+Kit+ (LSK) cells
PRJNA952194 | ENA
UnknownIRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay.
Not available
S-EPMC8553338 | biostudies-literature
GenomicsImmune homeostasis and regulation of the Interferon pathway require myeloid-derived Regnase-3
Immune homeostasis and regulation of the Interferon pathway require myeloid-derived Regnase-3
PRJNA530962 | ENA
ProteomicsPhosphorylation-dependent Regnase-1 interactome
In this study, we exploited interactome-based approach to isolate Regnase-1 protein complexes and found that TLR-ligand, IL-1β, or IL-17 stimulation induces formation of the Regnase-1-14-3-3 or -βTRCP complex in a mutually exclusive manner.
ORGANISM(S): Homo Sapiens (human) 
2021-10-12 | PXD026561 | JPOST Repository
GenomicsCrosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression
Crosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression
PRJNA1002277 | ENA
GenomicsCrosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression
Crosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression
PRJNA1001954 | ENA
TranscriptomicsEffect of loss of Regnase-1 and Regnase-3 on the transcriptional profile in mouse Lin–Sca1+Kit+ (LSK) cells
Regulation of lineage biases in hematopoietic stem and progenitor cells (HSPCs) is pivotal for balanced hematopoietic output. However, little is known about the mechanism behind lineage choice in HSPCs. Here, we show that mRNA decay factors Regnase-1 (Zc3h12a) and Regnase-3 (Zc3h12c) are critical fo...
ORGANISM(S): Mus musculus 
2024-02-09 | GSE228923 | GEO
TranscriptomicsImmune homeostasis and regulation of the Interferon pathway require myeloid-derived Regnase-3
The RNase Regnase-1 is a master RNA regulator in macrophages and T cells that degrades cellular and viral RNA upon NF-kB signaling. The roles of the other Regnase family-members remain largely unknown. Here, we analyze Regnase-3 deficient mice, which develop hypertrophic lymph nodes. We used various...
ORGANISM(S): Mus musculus 
2019-04-05 | GSE129325 | GEO
UnknownImmune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
Not available
S-EPMC6605757 | biostudies-literature
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