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TranscriptomicsTranscription profiling of S. cerevisiae response to carbon limitation in aerobic chemostat cultures
Zinc is indispensable for the catalytic activity and structural stability of many proteins, and its deficiency can have severe consequences for microbial growth in natural and industrial environments. For example, Zn depletion in wort negatively affects beer fermentation and quality. Several studies...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-8088 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae response to nitrogen limitation in chemostat culture
Zinc is indispensable for the catalytic activity and structural stability of many proteins, and its deficiency can have severe consequences for microbial growth in natural and industrial environments. For example, Zn depletion in wort negatively affects beer fermentation and quality. Several studies...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-8089 | biostudies-arrayexpress
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to zinc limitation in chemostat cultures
Zinc is indispensable for the catalytic activity and structural stability of many proteins, and its deficiency can have severe consequences for microbial growth in natural and industrial environments. For example, Zn depletion in wort negatively affects beer fermentation and quality. Several studies...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-15 | E-GEOD-8035 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to fermentative conditions
The capacity of respiring cultures of Saccharomyces cerevisiae to instantaneously switch to fast alcoholic fermentation upon a transfer to anaerobic sugar-excess conditions is a key characteristic of Saccharomyces cerevisiae in many of its industrial applications. This transition was studied by expo...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8187 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to investigate formaldehyde as source of free-energy during growth on glucose
Previously, it has been demonstrated that formate can be utilized by Saccharomyces cerevisiae as additional energy source using cells grown in a glucose-limited chemostat. Here, we investigated utilization of formaldehyde as co-substrate. Since endogenous formaldehyde dehydrogenase activities were i...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8902 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Saccharomyces cerevisiae reveals the regulation of reserve carbohydrate metabolism in S cerevisiae in response to nutrient availability
In Saccharomyces cerevisiae, glycogen and trehalose are important reserve carbohydrates that accumulate under nutrient limitation in batch cultures. An inherent draw-back of batch studies is that specific growth rate and substrate and product concentrations are variable over time and between culture...
ORGANISM(S): Saccharomyces cerevisiae 
2009-09-05 | E-GEOD-15465 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast to investigate the involvement of Snf7 and Rim101 in regulation of TIR1 and anaerobically up-regulated genes
Despite the scientific and applied interest in anaerobic metabolism of Saccharomyces cerevisiae, not all genes whose transcription is up-regulated under anaerobic conditions have yet been linked to known transcription factors. Experiments with a reporter construct in which the promoter of the anaero...
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-02 | E-GEOD-18128 | biostudies-arrayexpress
TranscriptomicsCCAAT/enhancer-binding protein alpha target genes in myeloid progenitor cells uncovered by chromatin IP
CCAAT/enhancer-binding protein alpha (C/EBPM-NM-1) is a lineage-specific transcription factor that directs development of granulocytes. To obtain insights into the genome-wide transcriptome of wild type C/EBPM-NM-1, we have performed chromatin immunoprecipitation on DNA promoter microarrays (ChIP-ch...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-19321 | biostudies-arrayexpress
TranscriptomicsPredicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1
Mesenchymal stromal cells (hMSCs) are advancing into the clinic but the therapeutic efficacy of hMSCs faces the problem of donor variability. In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation. To th...
ORGANISM(S): Homo sapiens 
2018-10-04 | E-MTAB-7210 | biostudies-arrayexpress
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