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Proteomicsβ-OHB Reduces Reinstatement of Cocaine Conditioned Place Preference Through Hippocampal CaMKII-α β-Hydroxybutyrylation
Studies have shown the therapeutic effects of a ketogenic diet (KD) on epilepsy, but the effect of KD on drug reinstatement is largely unclear. This study aims to investigate whether KD consumption possesses therapeutic potential for cocaine reinstatement and the molecular mechanism. We find that KD...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-30 | PXD037321 | Pride
Β-ohb  cocaine reinstatement  camkii-α β-hydroxybutyrylation 
ProteomicsUBE3A reinstatement restores behavior and proteome in an Angelman Syndrome mouse model of Imprinting Defects
Abstract Background: Angelman Syndrome (AS) is a severe neurodevelopmental disorder with only symptomatic treatment currently available. The primary cause of AS is loss of functional UBE3A protein. This can be caused by deletions in the maternal 15q11-q13 region, maternal AS-imprinting center defect...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-04-16 | MSV000097644 | MassIVE
GenomicsUBE3A reinstatement restores behavior and proteome in an Angelman syndrome mouse model of imprinting defects
UBE3A reinstatement restores behavior and proteome in an Angelman syndrome mouse model of imprinting defects
PRJNA1200029 | ENA
UnknownNucleus accumbens GLT-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement.
Not available
S-EPMC6383073 | biostudies-literature
UnknownReinstatement and transformation of memory traces for recognition.
Not available
S-EPMC11838014 | biostudies-literature
UnknownEnhanced reinstatement of naturalistic event memories due to hippocampal-network-targeted stimulation.
Not available
S-EPMC8044012 | biostudies-literature
UnknownEscalation and reinstatement of fentanyl self-administration in male and female rats.
Not available
S-EPMC10332850 | biostudies-literature
UnknownSmoking abstinence and reinstatement effects in adolescent cigarette smokers.
Not available
S-EPMC2902909 | biostudies-literature
TranscriptomicsUBE3A reinstatement restores behavior and proteome in an Angelman syndrome mouse model of imprinting defects
Angelman Syndrome (AS) is a severe neurodevelopmental disorder with only symptomatic treatment currently available. Besides mutations within the UBE3A gene, AS is caused by deletions, imprinting center defects (mICD) or uniparental disomy of chromosome 15 (UPD). Current mouse models are Ube3a-centri...
ORGANISM(S): Mus musculus 
2025-09-03 | GSE284678 | GEO
UnknownReinstatement of distributed cortical oscillations occurs with precise spatiotemporal dynamics during successful memory retrieval.
Not available
S-EPMC4284613 | biostudies-literature
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