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TranscriptomicsHalobacterium salinarum NRC-1 total RNA hybridization of TFBd overexpression versus Reference sample
Total RNA hybridizations of Halobacterium salinarum NRC-1 total RNA versus a strain overexpressing TFBd were compared to verify the transcriptome landscape changes. Comparison with TFBd binding sites localized using ChIP-chip data and MeDiChI algorithm (Reiss et al, 2008) allowed observation that TF...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-15788 | biostudies-arrayexpress
TranscriptomicsHalobacterium sp. NRC-1 ChIP-chip for TFBa, TFBd and TFBf, high resolution array
A detailed map of genomic locations where TFs bind DNA and modulate transcription is essential to model mechanisms of gene regulation on a systems-scale. Chromatin immunoprecipitation of transcription complexes coupled to microarray (ChIP-chip (Ren et al, 2000)) or sequencing (ChIP-seq (Robertson et...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-15786 | biostudies-arrayexpress
TranscriptomicsCoordination of frontline defense mechanisms under severe oxidative stress.
Oxidative stress (OS) results from genetic defects or stressful environmental challenges that cause unchecked production of reactive oxygen species (ROS). OS has been implicated in many diseases due to its wide ranging damage to nucleic acids, proteins and lipids. Using Halobacterium salinarum NRC...
ORGANISM(S): Halobacterium salinarum 
2010-05-26 | E-GEOD-17515 | biostudies-arrayexpress
TranscriptomicsHalobacterium salinarum NRC-1 growth curve
Halobacterium salinarum NRC-1 was grown in CM media, at 37oC in a waterbath with agitation of 125 rpm under constant light. Analysis of transcriptional changes during growth, in addition to mapping of transcriptome structure under the same conditions, provided interesting insights about regulatory l...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-12977 | biostudies-arrayexpress
TranscriptomicsHalobacterium salinarum NRC-1 conditional ChIP-chip for transcription initiation factor IIB 4 (TFBd)
Conditional ChIP-chip for TFBd at different growth stages. cmyc-tagged TFBd was immunoprecipitated at different growth stages (early log, stationary and late stationary phases) and hybridized to microarrays.
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-16 | E-GEOD-13108 | biostudies-arrayexpress
TranscriptomicsHalobacterium salinarum NRC-1 growth curve, tiling arrays
Experimentally mapped transcriptome structure of H. salinarum NRC-1 by hybridizing total RNA (including RNA species <200 nt) to genome-wide high-density tiling arrays (60 mer probes with 40 nt overlap between contiguous probes). H. salinarum NRC-1 presents a number of interesting switches in metabol...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-12923 | biostudies-arrayexpress
Proteomics,MultiomicsHalo_itraq12
Proteins harvested from cultures recovering from 0Gy (control) or 2500Gy (experimental) of gamma irradiation stress and labeled with iTRAQ, multiplex sample #12 with three time points 30, 40, 60 min during recovery compared against common reference; Whitehead et al., 2006 Mol Syst Biol. 2(47). Repli...
ORGANISM(S): Halobacterium Nrc-1 (halobacterium) 
2006-12-31 | PAe000259 | PeptideAtlas
Proteomics,MultiomicsHalo_itraq11
Proteins harvested from cultures recovering from gamma irradiation stress and labeled with iTRAQ, multiplex sample #11 with three time points 30, 40, and 60 min during recovery compared against common reference; Whitehead et al., 2006 Mol Syst Biol. 2(47).
ORGANISM(S): Halobacterium Nrc-1 (halobacterium) 
2006-12-31 | PAe000245 | PeptideAtlas
UnknownPTBP1 variants displaying altered nucleocytoplasmic distribution are responsible for a neurodevelopmental disorder with skeletal dysplasia.
Not available
S-EPMC12618068 | biostudies-literature
UnknownSeverity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulation.
Not available
S-EPMC4309077 | biostudies-literature
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