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ProteomicsMitochondrial DNA affects tau expression and phosphorylation in Alzheimers Disease and aging in humans and cybrid cell lines
We investigate the role of mitochondrial DNA in Alzheimers Disease pathology using human cybrid cell lines and investigate the relationships between biomarker expression from cybrids and clinically relevant outcomes from the same individuals. Proteomic analysis of cybrids showed significant alterati...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-11 | MSV000096065 | MassIVE
ProteomicsMarkers of neutrophil degranulation in the lung microenvironment linked to idiopathic pulmonary fibrosis severity and survival
Idiopathic pulmonary fibrosis (IPF) leads to progressive loss of lung function and mortality. Understanding mechanisms and markers of lung injury in IPF is paramount to improving outcomes for these patients. Despite the lack of systemic involvement in IPF, many analyses focus on identifying circulat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-05-29 | MSV000098032 | MassIVE
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