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TranscriptomicsGlobal changes in gene expression in dermal fibroblasts with in vivo and in vitro deletion of the RBP-Jk gene
It is currently unclear whether tissue changes surrounding multifocal epithelial tumors are a cause or consequence of cancer. Here, we provide evidence that loss of mesenchymal Notch/CSL signaling causes tissue alterations, including stromal atrophy and inflammation, which precede and are potent tri...
ORGANISM(S): Mus musculus 
2012-06-11 | E-GEOD-36359 | biostudies-arrayexpress
MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
TranscriptomicsHalobacterium sp. NRC-1 ChIP-chip for TFBa, TFBd and TFBf, high resolution array
A detailed map of genomic locations where TFs bind DNA and modulate transcription is essential to model mechanisms of gene regulation on a systems-scale. Chromatin immunoprecipitation of transcription complexes coupled to microarray (ChIP-chip (Ren et al, 2000)) or sequencing (ChIP-seq (Robertson et...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-17 | E-GEOD-15786 | biostudies-arrayexpress
UnknownJUN mediates glucocorticoid resistance by stabilizing HIF1a in T cell acute lymphoblastic leukemia.
Not available
S-EPMC10661119 | biostudies-literature
UnknownDirect regulation of FOXK1 by C-jun promotes proliferation, invasion and metastasis in gastric cancer cells.
Not available
S-EPMC5260906 | biostudies-literature
UnknownDevelopment of a loop-mediated isothermal amplification assay for rapid detection of subgroup J avian leukosis virus.
Not available
S-EPMC2884476 | biostudies-literature
TranscriptomicsA module-based translational strategy shows a central role for S100A4 in allergy
The involvement of thousands of genes complicates the identification of clinically relevant candidate genes in common diseases. We hypothesized that genes co-regulated with a key gene in allergy, IL13, would form a module that could help to discover novel candidate genes. We identified a Th2 cell mo...
ORGANISM(S): Homo sapiens 
2014-02-05 | E-GEOD-46333 | biostudies-arrayexpress
UnknownNDV-induced autophagy enhances inflammation through NLRP3/Caspase-1 inflammasomes and the p38/MAPK pathway.
Not available
S-EPMC10240457 | biostudies-literature
Unknownc-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82.
Not available
S-EPMC2825421 | biostudies-literature
UnknownChondrogenic medium in combination with a c-Jun N-terminal kinase inhibitor mediates engineered cartilage regeneration by regulating matrix metabolism and cell proliferation.
Not available
S-EPMC10640392 | biostudies-literature
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