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ProteomicsNovel diagnostic biomarkers in serum identify patients with OSCC
Purpose No blood biomarkers to detect early OSCC without clinical signs exist - diagnosis is solely based on histology of a visible tumor. Most OSCC patients are diagnosed at advanced stage, which leads to significant morbidity and poor survival. If high-risk patients were identified with blood-base...
ORGANISM(S): Homo sapiens (Human) 
2018-04-25 | PXD005263 | Pride
Serum proteomics Multivariate analyses Oscc 
ProteomicsIn parallel proteins and glycopeptidomics: Novel diagnostic glycopeptide biomarkers in serum identify patients with early-stage oropharyngeal squamous cell carcinoma
This is the glycopeptide part of the above project. Purpose: No blood-based biomarkers to detect OPSCC early before symptoms develop or before clinically visible. Diagnosis is solely based on histology of a visible tumour. Most OPSCC patients are diagnosed at an advanced stage, which leads to signi...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016709 | Pride
Glycopeptidomics Proteomics Head and neck cancer Mass spectrometry Serum Opscc 
ProteomicsPatients with early stage oropharyngeal squamous cell carcinoma can be identified with label-free serum proteomics
Increased incidence of oropharyngeal squamous cell carcinoma (OPSCC) is mainly related to Human Papilloma Virus (HPV) infection. As OPSCCs are often diagnosed at an advanced stage, mortality and morbidity remain high. There are no diagnostic biomarkers for early stage detection of OPSCC. Serum from...
ORGANISM(S): Homo sapiens (Human) 
2018-07-11 | PXD008445 | Pride
Oropharyngeal squamous cell carcinoma  serum proteomics  multivariate data analysis  complement factor h-related protein 2  myosin regulatory light chain 12a 
ProteomicsIn-parallel proteomics and glycopeptidomics: Novel diagnostic glycopeptide biomarkers in serum identify patients with early-stage oropharyngeal squamous cell carcioma
This is the proteomics part of the above project. Purpose: No blood-based biomarkers to detect OPSCC early before symptoms develop or before clinically visible. Diagnosis is solely based on histology of a visible tumour. Most OPSCC patients are diagnosed at an advanced stage, which leads to signific...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016727 | Pride
Glycopeptidomics Proteomics Head and neck cancer Mass spectrometry Serum Opscc 
ProteomicsQuantitative Label Free Ultra Definition Mass-Spectrometry Provides Novel Data on the Proteomic Signature of Oral Squamous Cell Carcinoma
There are no early detection biomarkers or prognostic markers for oral squamous cell carcinoma (OSCC) thus many are detected late, with unpredictable disease course. Using systems level analysis on shotgun proteomics with quantitative label-free ultra-definition mass spectrometry, our study aims to ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD009244 | Pride
Oscc Tongue cancer Label-free proteomics Tissue proteomics 
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