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TranscriptomicsHPV-related methylation in Oropharyngeal squamous cell carcinomas (OPSCC)
Using MCIp, we enriched highly methylated DNA from a normal mucosa control and from three OPSCC patient subgroups regarding the HPV status: group A, DNA-RNA- (Tu1-Tu5); group B, DNA+RNA- (Tu6-Tu10); group C, DNA+RNA+ (Tu11-Tu15). 3 groups of tumor biopsies, 5 samples each regarding HPV status: DNA-R...
ORGANISM(S): Homo sapiens 
2013-09-16 | E-GEOD-41152 | biostudies-arrayexpress
ProteomicsIn-parallel proteomics and glycopeptidomics: Novel diagnostic glycopeptide biomarkers in serum identify patients with early-stage oropharyngeal squamous cell carcioma
This is the proteomics part of the above project. Purpose: No blood-based biomarkers to detect OPSCC early before symptoms develop or before clinically visible. Diagnosis is solely based on histology of a visible tumour. Most OPSCC patients are diagnosed at an advanced stage, which leads to signific...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016727 | Pride
Glycopeptidomics Proteomics Head and neck cancer Mass spectrometry Serum Opscc 
ProteomicsIn parallel proteins and glycopeptidomics: Novel diagnostic glycopeptide biomarkers in serum identify patients with early-stage oropharyngeal squamous cell carcinoma
This is the glycopeptide part of the above project. Purpose: No blood-based biomarkers to detect OPSCC early before symptoms develop or before clinically visible. Diagnosis is solely based on histology of a visible tumour. Most OPSCC patients are diagnosed at an advanced stage, which leads to signi...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD016709 | Pride
Glycopeptidomics Proteomics Head and neck cancer Mass spectrometry Serum Opscc 
TranscriptomicsTranscription profiling by array of HPV16-positive OPSCC samples from human donors
mRNA array of HPV16-positive OPSCC with known viral integration status
ORGANISM(S): Homo sapiens 
2018-10-20 | E-MTAB-6350 | biostudies-arrayexpress
ProteomicsThe HLA-ligandome of oropharyngeal squamous cell carcinomas reveals shared tumor-exclusive peptides for semi-personalized vaccination
Oropharyngeal squamous cell carcinoma (OPSCC) is diagnosed in 93,000 patients worldwide per year and 51,000 annual deaths can be attributed to this disease. OPSCCs are either human papillomavirus associated (HPV-positive) cancers or non-virally induced, primarily tobacco and alcohol associated (HPV-...
ORGANISM(S): Homo sapiens (Human) 
2023-02-27 | PXD033383 | Pride
Hpv Hla Tumor-associated antigen Oropharyngeal squamous cell carcinoma Mass spectrometry Opscc Immunopeptidome Immunopeptidomics 
Methylation profilingHPV-related methylation in Oropharyngeal squamous cell carcinomas (OPSCC)
Using MCIp, we enriched highly methylated DNA from a normal mucosa control and from three OPSCC patient subgroups regarding the HPV status: group A, DNA-RNA- (Tu1-Tu5); group B, DNA+RNA- (Tu6-Tu10); group C, DNA+RNA+ (Tu11-Tu15).
ORGANISM(S): Homo sapiens 
2013-09-16 | GSE41152 | GEO
TranscriptomicsLINE-1 methylation as survival predictive factor in patients with stage III-IV oropharyngeal squamous cell carcinoma
Nowadays, risk stratification for oropharyngeal squamous cell carcinoma (OPSCC) is based on HPV status, tobacco smoking, and tumor stage. Although HPV positivity represents a strong prognostic factor for both reduced risk of relapse, and improved survival, there is a subset of HPV-positive OPSCC pat...
ORGANISM(S): Homo sapiens 
2023-02-21 | E-MTAB-12032 | biostudies-arrayexpress
TranscriptomicsLINE-1 methylation as survival predictive factor in patients with stage III-IV oropharyngeal squamous cell carcinoma
Nowadays, risk stratification for oropharyngeal squamous cell carcinoma (OPSCC) is based on HPV status, tobacco smoking, and tumor stage. Although HPV positivity represents a strong prognostic factor for both reduced risk of relapse, and improved survival, there is a subset of HPV-positive OPSCC pat...
ORGANISM(S): Homo sapiens 
2022-07-14 | E-MTAB-11152 | biostudies-arrayexpress
GenomicsDetermine differences in gene expression between OPSCC cell lines with different sensitivity to IR
Determine differences in gene expression between OPSCC cell lines with different sensitivity to IR
PRJNA644620 | ENA
UnknownComprehensive Analysis of VEGFR2 Expression in HPV-Positive and -Negative OPSCC Reveals Differing VEGFR2 Expression Patterns.
Not available
S-EPMC8533978 | biostudies-literature
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