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ProteomicsDengue Virus NS1 Replicon - Dengue virus (DENV) is a major human pathogen that belongs to the flavivirus genus
Dengue virus (DENV) is a major human pathogen that belongs to the flavivirus genus. Among non-structural viral proteins, NS1 is an enigmatic factor that is exclusively encoded by members of the flavivirus genus within the Flaviviridae family and accomplishes different functions during DENV infection...
ORGANISM(S): Homo sapiens (Human) Dengue virus 
2017-11-29 | PXD008120 | Pride
Ns1 Human cells Replicon Dengue virus 
TranscriptomicsTranscription profiling of human hepatoma-derived Huh7 cells carrying the Hepatitus C virus clone 21-5, cells in which the virus has been eliminated and parental cells
Hepatitis C virus (HCV) RNA synthesis and protein expression affect cell homeostasis by modulation of gene expression. The impact of HCV replication on global cell transcription has not been fully evaluated. Thus, we analysed the expression profiles of different clones of human hepatoma-derived Huh7...
ORGANISM(S): Homo sapiens 
2008-06-27 | E-MEXP-1686 | biostudies-arrayexpress
MetabolomicsCreation and Characterization of a Genomically Hybrid Strain in the Nitrogen-Fixing Symbiotic Bacterium Sinorhizobium meliloti
Many bacteria, often associated with eukaryotic hosts and of relevance for biotechnological applications, harbor a multipartite genome composed of more than one replicon. Biotechnologically relevant phenotypes are often encoded by genes residing on the secondary replicons. A synthetic biology approa...
2021-03-17 | MTBLS576 | MetaboLights
TranscriptomicsTranscription profiling of human hepatitis C virus replicon cell line treated with interferon-alpha 2a in a time series
Temporal analysis of genes regulated by Interferon-alpha 2a in a HCV (Hepatitis C Virus) Replicon Cell line
ORGANISM(S): Homo sapiens 
2011-11-08 | E-MEXP-714 | biostudies-arrayexpress
TranscriptomicsCREB3L1 Target Genes in Response to Hepatitis C Replicon Infection
Membrane-bound transcription factor CREB3L1 undergoes Regulated Intramembrane Proteolysis (RIP) in response to Hepatitis C infection. RIP activates CREB3L1 so that it can prevent the growth of HCV infected cells through the action of downstream genes. We over-expressed a truncated form of CREB3L1 ...
ORGANISM(S): Homo sapiens 
2011-05-01 | E-GEOD-25157 | biostudies-arrayexpress
ProteomicsClostridium autoethanogenum isopropanol production via native plasmid pCA replicon
Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon
ORGANISM(S): Clostridium Autoethanogenum (ncbitaxon:84023) 
2022-05-10 | MSV000089452 | MassIVE
TranscriptomicsTranscription profiling of Drosophila cells to FHV RNA1 replicon expression (replicon experiment)
Virus infections induce cellular gene up and down regulation, and these changes often provide clues to cellular pathways utilized by viruses. We used microarrays to examine the transcriptional responses of cultured Drosophila S2 cells to Flock House virus (FHV) replicon induction. Experiment Overall...
ORGANISM(S): Drosophila melanogaster 
2009-04-11 | E-GEOD-15467 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of Drosophila cells to FHV RNA1 replicon expression (replicon experiment)
Virus infections induce cellular gene up and down regulation, and these changes often provide clues to cellular pathways utilized by viruses. We used microarrays to examine the transcriptional responses of cultured Drosophila S2 cells to Flock House virus (FHV) replicon induction.
ORGANISM(S): Drosophila melanogaster 
2009-04-01 | GSE15467 | GEO
GenomicsEscherichia coli
mini replicon
PRJDB15168 | ENA
TranscriptomicsExpression data from Tp80-Treated HCV replicon cell, Huh7/RepFeo.
Tp80 is a novel antiviral compound. Antiviral mechanism of Tp80 is the inhibition of the viral genome replication through the recoverly of GPx2 expression downregulated by HCV infection. We used microarrays to evaluated the effect of Tp80 on the transcriptome of HCV replicon cells, compared with Non...
ORGANISM(S): Homo sapiens 
2016-12-20 | GSE60488 | GEO
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