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Stress-triggered hematopoietic stem cell proliferation relies on Primpol-mediated repriming
Stem cell division is linked to tumorigenesis by yet-elusive mechanisms. The hematopoietic system reacts to stress by triggering stem and progenitor cell (HSPC) proliferation, which can be accompanied by chromosomal breakage in activated haematopoietic stem cells (HSCs). However, whether these lesio...
ORGANISM(S): Mus musculus 
2023-06-14 | GSE212580 | GEO
SILAC-IP and mass spectrometric analysis of Primpol to determine phosphorylaton of a specific serine residue
ORGANISM(S): Homo sapiens (Human) 
2021-12-27 | PXD027918 | Pride
Repriming limits R-loop formation at DNA secondary structures during S phase
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