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TranscriptomicsGenome-wide analysis of gene expression perturbed by reptin shRNA in MCF7 subjected to normoxic and hypoxic conditions
In order to investigate the role of reptin methylation on the expression of hypoxia-responsive genes across the whole genome, we performed a microarray analysis from RNAs isolated from MCF7 cells expressing either control shRNA (shRNA) or reptin shRNA (shreptin) in normoxic and hypoxic conditions. M...
ORGANISM(S): Homo sapiens 
2010-07-13 | E-GEOD-15530 | biostudies-arrayexpress
ProteomicsAn inter-subunit protein-protein interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin
Reptin forms multiple inter-subunit protein-protein interaction contacts. Rate-limiting motifs in ligand-dependent oligomer assembly are not defined. We set up a Reptin-self peptide scan assay to identify functional protein-protein interfaces that dominate in Reptin self assembly. The most dominant ...
ORGANISM(S): Homo sapiens (Human) 
2019-04-23 | PXD008226 | Pride
Hdx mass spectrometry Oligomer assembly Protein-protein interaction Reptin 
TranscriptomicsGenome-wide analysis of gene expression perturbed by reptin shRNA in MCF7 subjected to normoxic and hypoxic conditions
In order to investigate the role of reptin methylation on the expression of hypoxia-responsive genes across the whole genome, we performed a microarray analysis from RNAs isolated from MCF7 cells expressing either control shRNA (shRNA) or reptin shRNA (shreptin) in normoxic and hypoxic conditions.
ORGANISM(S): Homo sapiens 
2010-07-13 | GSE15530 | GEO
UnknownReptin regulates DNA double strand breaks repair in human hepatocellular carcinoma.
Not available
S-EPMC4398330 | biostudies-literature
UnknownReptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility.
Not available
S-EPMC3732945 | biostudies-literature
UnknownNegative regulation of hypoxic responses via induced Reptin methylation.
Not available
S-EPMC4651011 | biostudies-literature
UnknownArchitecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes.
Not available
S-EPMC2577609 | biostudies-literature
UnknownIdentification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly.
Not available
S-EPMC2291539 | biostudies-literature
UnknownThe emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape.
Not available
S-EPMC4201591 | biostudies-literature
UnknownWAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes.
Not available
S-EPMC4730548 | biostudies-literature
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