Degenerative retinal diseases like age-related macular degeneration (AMD) are the leading cause of blindness. Cell transplantation showed promising therapeutic effect for such diseases, and retinal progenitor cell (RPC) derived from embryonic stem cell (ESC) is one of the sources of such donor cells...
Microarray expression analysis of mouse ESCs treated with the MYCi 10058-F4. Mouse ESCs were analysed after 60h of treatment with DMSO or 10058-F4 (MYCi). The MYCi⇒Released (Resc) group was treated with 10058-F4 for 60h, followed by withdrawal of the inhibitor and culture in 2i medium for addition...
Trypanosoma brucei requires extensive uridine insertion and deletion RNA editing of most of their mitochondrial transcripts to generate translatable open reading frames. The RNA editing substrate binding complex (RESC) serves as the scaffold that coordinates the protein-protein and protein-RNA inter...
