Sort   by:  
 Page size 
ProteomicsAn integrative multi-omics analysis reveals microRNA-143 as potential therapeutics to attenuate retinal angiogenesis
Retinal neovascularization is a severe complication of several neovascular retinal diseases, including proliferative diabetic retinopathy, central retinal vein occlusion and retinopathy of prematurity. MicroRNAs (miRNAs) are master regulators of gene expression that play an important role in retinal...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD029706 | Pride
Microrna Endothelial cells Oxygen-induced retinopathy Retinal neovascularization Next-generation sequencing 
ProteomicsMonocyte histone lactylation-regulated exosomal periostin promotes retinal neovascularization
Exosomes serve as signaling messengers that facilitate intercellular communication through delivering molecular cargo. Here, we observed elevated levels of exosomal periostin (POSTN) in blood plasma of patients with proliferative diabetic retinopathy (PDR). Monocytes-derived exosomal POSTN was incre...
ORGANISM(S): Homo Sapiens 
2025-01-20 | PXD059956 |
ProteomicsSerine supplementation suppresses hypoxia-induced pathological retinal angiogenesis
Pathological retinal angiogenesis with irregular and fragile vessels (also termed as neovascularization, a response to hypoxia and dysmetabolism) is a leading cause of vision loss in all age groups driven in part by unmet metabolic demand from retinal neurons. Sustaining neural retinal metabolism wi...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD056490 | Pride
Retinopathy of prematurity Serine Neovascularization Angiogenesis Retina 
GenomicsA local neuronal clock regulates retinal angiogenesis and neovascularization
A local neuronal clock regulates retinal angiogenesis and neovascularization
PRJNA854612 | ENA
GenomicsChronic HIF1A activity in rod photoreceptors causes type 3 neovascularization and retinal atrophy
Chronic HIF1A activity in rod photoreceptors causes type 3 neovascularization and retinal atrophy
PRJNA1257309 | ENA
GenomicsTranscriptional Comparison of Human and Murine Retinal Neovascularization
Transcriptional Comparison of Human and Murine Retinal Neovascularization
PRJNA981457 | ENA
GenomicsTargeting ATF6 Reduces Pathological Neovascularization and Improves Visual Outcomes in Retinal Disease Models
Targeting ATF6 Reduces Pathological Neovascularization and Improves Visual Outcomes in Retinal Disease Models
PRJNA1236858 | ENA
ProteomicsMitochondrial control of hypoxia-induced pathological retinal angiogenesis
Objective: Pathological retinal angiogenesis is vision threatening. In mouse oxygen-induced retinopathy (OIR) we sought to define mitochondrial respiration changes longitudinally during hyperoxia-induced vessel loss and with hypoxia-induced neovascularization (NV), and test interventions to address ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD051410 | Pride
Lc-msms Retinal angiogenesis Neovascularization Mitochondrial respiration Hypoxia Retina Oxygen-induced retinopathy 
TranscriptomicsRNA-seq of choroid and retina in tree shrews with choroidal neovascularization
In order elucidate the key signaling pathways in choroidal neovascularization, we induced choroidal angiogenesis by laser photocoagulation in 12 tree shrews and obtained mRNA profiles of their choroids and retinas by high-throughput transcriptome sequencing. Gene ontology(GO) and kyoto encyclopedia ...
ORGANISM(S): Tupaia chinensis 
2021-03-21 | E-MTAB-10198 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling In Murine Retina Neovascularization Models
In order to find out the vital genes during retinal neovascularization (RNV), we set up OIR (oxygen-induced retinopathy; induced with 75%±2% oxygen) and wild-type C57BL/6J murine models. We observed the retinal vascular growth process daily both in OIR and wild-type mice through retinal flat-mount,...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-38762 | biostudies-arrayexpress
Sort   by:  
 Page size