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UnknownATP disrupts lipid-binding equilibrium to drive retrograde transport critical for bacterial outer membrane asymmetry.
Not available
S-EPMC8685716 | biostudies-literature
TranscriptomicsEffects of GOLPH3 knock-out on the mouse liver transcriptomic profile
The Golgi complex serves as the central hub of the biosynthetic pathway, where anterograde and retrograde trafficking converge. How cargo and Golgi-resident proteins traverse this organelle has long been debated. Recent studies have identified a molecular machinery that sorts resident proteins into ...
ORGANISM(S): Mus musculus 
2026-04-23 | GSE327245 | GEO
UnknownForward or backward, that is the question: phospholipid trafficking by the Mla system.
Not available
S-EPMC10212509 | biostudies-literature
ProteomicsOuter membrane vesicle and outer membrane of Haemophilus influenzae Rd KW20, Rd ∆yrbE and Rd ∆vacJ
Bacterial outer membrane vesicles (OMVs) have important biological roles in pathogenesis and intercellular interactions, but a general mechanism of OMV formation is lacking. Here we show that the VacJ/Yrb ABC transport system, a proposed phospholipid (PL) transporter, is involved in OMV formation. D...
ORGANISM(S): Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 
2016-01-27 | PXD003249 | Pride
Mla pathway Omv Haemophilus influenzae Retrograde lipid trafficking system Om 
UnknownStructure and mechanism of the bacterial lipid ABC transporter, MlaFEDB.
Not available
S-EPMC9509461 | biostudies-literature
UnknownRetromer forms low order oligomers on supported lipid bilayers.
Not available
S-EPMC7443500 | biostudies-literature
GenomicsEffects of GOLPH3 knock-out on the mouse liver transcriptomic profile
Effects of GOLPH3 knock-out on the mouse liver transcriptomic profile
PRJNA1450033 | ENA
ProteomicsAtg9 resides on a unique population of small vesicles in presynaptic nerve terminals
In neurons, autophagosomes are mainly initiated in distal axons, followed by maturation during retrograde transport. Autophagosomal growth depends on the supply of membrane lipids which requires small vesicles containing Atg9, a lipid scramblase essential for autophagocytosis. Here, we show that Atg...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-01-17 | PXD041702 | Pride
Neurons Immunoisolation Atg9 
UnknownExpression Analysis of CB2-GFP BAC Transgenic Mice.
Not available
S-EPMC4583291 | biostudies-literature
ProteomicsToxoplasma gondii LC-MS/MS - Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection
The phylum Apicomplexa comprises an ancient group of early divergent eukaryotes, including some of the most deadly pathogens of medical and veterinary importance. Plasmodium species are responsible for malaria, which causes as many as 700,000 deaths per year, while Toxoplasma gondii chronically infe...
ORGANISM(S): Toxoplasma gondii RH 
2016-04-12 | PXD003603 | Pride
Toxoplasma gondii lc-ms/ms 
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