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MetabolomicsMyocardial Rev-erb-mediated diurnal metabolic rhythm( Part1/3)
Not available
ORGANISM(S): Mus musculus 
ST001915 | MetabolomicsWorkbench
GenomicsREV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis
REV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis
PRJNA760305 | ENA
TranscriptomicsREV1 promotes lung tumorigenesis by activating the Rad18/SERTAD2 axis
REV1 is the central member of the family of TLS polymerases, which participate in various DNA damage repair and tolerance pathways, including translesion DNA synthesis, and play a significant role in maintaining genomic stability. However, the role of REV1 in tumors is rarely reported. In this study...
ORGANISM(S): Homo sapiens 
2022-02-09 | GSE183332 | GEO
ProteomicsA role for the putative error-prone polymerase REV1 in DNA damage and antifungal drug resistance in Candida albicans
Antimicrobial-induced DNA damage, and subsequent repair via upregulation of DNA repair factors, including error-prone translesion polymerases, can lead to the increased accumulation of mutations in the microbial genome, and ultimately increased risk of acquired mutations associated with antimicrobia...
ORGANISM(S): Candida albicans (Yeast) 
2025-05-07 | PXD055008 | Pride
Candida albicans Rev1 Fungal 
GenomicsBrucella melitensis isolates from blood of Rev1 vaccinated pigs
Brucella melitensis isolates from blood of Rev1 vaccinated hoggets in Greece
PRJEB82706 | ENA
ProteomicsAnalysis of Rev1-dependent replication dynamics using isolation of proteins on nascent DNA
To study the influence of the Rev1 translesion synthesis enzyme on fork dynamics, we performed isolation of proteins on nascent DNA coupled with mass spectrometry (iPOND-MS). Wild-type and REV1-KO HEK293 Flp-In™/T-REx™ cells were used. Treatment with the G-quadruplex stabilizing agent pyridostatin (...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD061281 | Pride
Dna replication G-quadruplex Translesion synthesis 
UnknownREV1 Inhibition Enhances Radioresistance and Autophagy.
Not available
S-EPMC8582445 | biostudies-literature
UnknownStructures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction.
Not available
S-EPMC8589032 | biostudies-literature
TranscriptomicsEvaluation of the role of functional constraints on the integrity of an ultra conserved region in the genus Drosophila
Our results indicate that even in highly rearranged genomes like those of Diptera, unusually high levels of gene order conservation cannot be systematically attributed to functional constraints, which points to mechanisms more subtle and diverse than previously thought. 6 genotypes (REC, INV1, INV2,...
ORGANISM(S): Drosophila melanogaster 
2011-08-02 | E-GEOD-31120 | biostudies-arrayexpress
UnknownUSP9X-mediated REV1 deubiquitination promotes lung cancer radioresistance via the action of REV1 as a Rad18 molecular scaffold for cystathionine γ-lyase.
Not available
S-EPMC11131313 | biostudies-literature
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