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ProteomicsREV7 associates with ATRIP and FAM35A
REV7 is a remarkably multi-faceted protein with important and separable roles in multiple genome maintenance pathways including Trans-Lesion Synthesis, the Fanconi Anemia pathway, as well as p53 signaling and Double Stranded Break resection. To investigate novel functions and pathways involving REV7...
ORGANISM(S): Homo sapiens (Human) 
2026-01-22 | PXD072142 | Pride
Atrip Rev7 Fam35a 
Proteomics53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
53BP1 governs a specialized, context-specific branch of the classical non-homologous end joining DNA double-strand break repair pathway. Mice lacking 53bp1 (also known as Trp53bp1) are immunodeficient owing to a complete loss of immunoglobulin class-switch recombination, and reduced fidelity of long...
ORGANISM(S): Mus musculus (Mouse) 
2018-07-26 | PXD009650 | Pride
Rev7 shieldin 
GenomicsBiallelic inactivation of REV7/MAD2L2 in Fanconi anemia
Biallelic inactivation of REV7/MAD2L2 in Fanconi anemia
PRJEB14414 | ENA
ProteomicsTRIP13 Regulates DNA Repair Pathway Choice through REV7 Conformational Change
Tandem Affinity Purification of REV7 (MAD2B) from HeLa S3 cells.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-10-30 | MSV000084515 | MassIVE
UnknownREV7 in Cancer Biology and Management.
Not available
S-EPMC10046837 | biostudies-literature
UnknownREV7: Jack of many trades.
Not available
S-EPMC7611290 | biostudies-literature
UnknownREV7 directs DNA repair pathway choice.
Not available
S-EPMC8608404 | biostudies-literature
UnknownREV7-p53 interaction inhibits ATM-mediated DNA damage signaling.
Not available
S-EPMC11174130 | biostudies-literature
UnknownREV7 associates with ATRIP and inhibits ATR kinase activity.
Not available
S-EPMC12820532 | biostudies-literature
UnknownREV7 confers radioresistance of esophagus squamous cell carcinoma by recruiting PRDX2.
Not available
S-EPMC6398896 | biostudies-literature
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