Reverse genetic engineering

Show results for

Transcriptomics (5307)
Unknown (776)
Genomics (138)
Proteomics (55)
Metabolomics (35)
Other (3)

Organisms

Homo sapiens (1766)
Mus musculus (1025)
Rattus norvegicus (196)
Caenorhabditis elegans (141)
Saccharomyces cerevisiae (135)
Arabidopsis thaliana (127)
Drosophila melanogaster (85)
Escherichia coli (55)
Bos taurus (51)
Sus scrofa (51)
Gallus gallus (46)
Candida albicans (46)
Danio rerio (45)
Thermus thermophilus HB8 (31)
Streptococcus pneumoniae D39 (30)
Oncorhynchus mykiss (27)
Zea mays (26)
Schizosaccharomyces pombe (26)
Macaca mulatta (24)
Oryza sativa (21)
Mycobacterium tuberculosis (20)
Staphylococcus aureus (20)
Salmo salar (20)
Triticum aestivum (19)
Bacillus subtilis (18)
Plasmodium falciparum (17)
Sinorhizobium meliloti (17)
Canis lupus familiaris (16)
Daphnia magna (15)
Pseudomonas putida (15)

Organisms

Mus musculus (4)
Homo sapiens (4)
Rattus norvegicus (3)
Thermothelomyces thermophilus ATCC 42464 (2)
Nannochloropsis oceanica (2)
Saccharomyces cerevisiae (2)
Nannochloropsis sp. C95 (1)
Clostridium autoethanogenum (1)
Saccharomyces cerevisiae CEN.PK113-7D (1)
Escherichia coli str. K-12 substr. MG1655 (1)
Lyssavirus rabies (1)
Porcine epidemic diarrhea virus (1)
Xenopus laevis (1)
Drosophila melanogaster (1)
Escherichia coli (1)
Plasmodium falciparum (1)

Repository

biostudies-arrayexpress (5420)
pride (40)
ENA (36)
MetaboLights (35)
geo (14)
MassIVE (9)
EGA (2)
GPMDB (1)
jPOST (1)
PanoramaPublic (1)

Tissue

Cell culture (13)
Whole body (6)
Leaf (3)
Stem (2)
Spleen (2)
Epithelial cell (2)
T cell (2)
Mammary epithelial cell line (1)
Fetal cardiomyocyte (1)
Gametophyte (1)
Seedling (1)
Cartilage (1)
Breast cancer cell line (1)
Flower (1)
Plant cell (1)
Macrophage (1)
Skeletal muscle (1)
Prokaryotic cell (1)
Primary cell (1)
Permanent cell line cell (1)
Kidney (1)
Blood (1)

Disease

Normal (24)
Breast cancer (5)
Breast adenocarcinoma (3)
Melanoma (3)
Infiltrating ductal carcinoma (2)
Primary tumor (2)
Colon cancer (2)
Colon adenocarcinoma (2)
Colorectal adenocarcinoma (2)
None (2)
Control (2)
Neuroblastoma (2)
Multiple sclerosis (1)
Early onset preeclampsia (1)
HPV positive (1)
Lymphoblastic leukemia (1)
Osteosarcoma subtype fibroblastic (1)
Diabetes mellitus type 1 (1)
Pseudomonas aeruginosa rsmA mutant infected (1)
Breast Normal (1)
Hepatomegaly (1)
Epithelioid mesothelioma (1)
ER positive breast cancer (1)
Invasive pituitary adenoma (1)
Hepatocellular carcinoma-non tumorous region (1)
T. circumcincta infection (1)
Multibacillary (1)
B-cell chronic lymphocytic leukemia (1)
CUP (1)
Primary medulloblastoma (1)

Technology Type

Mass Spectrometry (40)
Mass spectrometry (25)
Shotgun proteomics (22)
Mass spectrometry assay (10)
Bottom-up proteomics (7)
Gel-based experiment (5)
Data-independent acquisition (4)
Top-down proteomics (2)
Affinity purification coupled with mass spectrometry proteomics (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
Illumina HiSeq 2000 (1)
NMR spectroscopy assay (1)
Affinity proteomics (1)
Immunopeptidomics (1)
SRM/MRM (1)
Data-dependent acquisition (1)

Instrument Platform

Illumina NovaSeq 6000 (33)
Illumina HiSeq 2000 (23)
NextSeq 500 (20)
Scanning hardware (19)
Illumina HiSeq 2500 (18)
Illumina HiSeq 4000 (15)
GenePix 4000B [Axon Instruments] (13)
Illumina NovaSeq X (13)
GenePix 4000A [Axon Instruments] (8)
Axon- GenePix4000B (7)
ScanArray Express HT [PerkinElmer] (7)
Illumina MiSeq (6)
GenePix Personal 4100A [Axon Instruments] (5)
418 [Affymetrix] (5)
G2565BA DNA microarray scanner [Agilent] (5)
NextSeq 2000 (5)
ScanArray 4000 [PerkinElmer] (4)
ScanArray Lite [PerkinElmer] (4)
ScanArray [PerkinElmer] (4)
ScanArray 6000 [Perkin Elmer] (4)
ScanArray scanning hardware (3)
GenePix Professional 4200A [Axon Instruments] (3)
DNBSEQ-G400 (3)
NextSeq 550 (3)
Microcentrifuge (2)
VersArray ChipReader [Bio-Rad Laboratories] (2)
FUJIFILM BAS-5000 scanning hardware (2)
Agilent G2565BA (2)
BAS-1800 [FUJIFILM] (2)
428 [Affymetrix] (2)

Publication Date

2010 (1026)
2013 (679)
2012 (670)
2011 (650)
2014 (569)
2015 (555)
2008 (276)
2016 (242)
2009 (235)
2007 (147)
2006 (71)
2005 (69)
2025 (57)
2017 (39)
2021 (36)
2022 (33)
2026 (31)
2018 (30)
2024 (28)
2020 (25)
2019 (21)
2023 (19)
2004 (11)

CHEBI ID

CHEBI:30915 (12)
CHEBI:15741 (10)
CHEBI:26078 (10)
CHEBI:30769 (10)
CHEBI:24266 (9)
CHEBI:25094 (9)
CHEBI:16708 (9)
CHEBI:15428 (9)
CHEBI:6650 (9)
CHEBI:16335 (9)
CHEBI:29016 (9)
CHEBI:18012 (9)
CHEBI:17992 (8)
CHEBI:16811 (8)
CHEBI:17752 (8)
CHEBI:24898 (8)
CHEBI:16610 (8)
CHEBI:16235 (8)
CHEBI:27266 (8)
CHEBI:17053 (8)
CHEBI:30887 (8)
CHEBI:18344 (8)
CHEBI:30754 (7)
CHEBI:28635 (7)
CHEBI:46961 (7)
CHEBI:17822 (7)
CHEBI:26271 (7)
CHEBI:18237 (7)
CHEBI:16040 (7)
CHEBI:22660 (7)

Metabolite Name

Serine (6)
Lysine (6)
Aspartate (6)
Arginine (6)
Histidine (6)
Phenylalanine (6)
Tyrosine (6)
Threonine (6)
Alanine (6)
Valine (6)
Isoleucine (6)
Leucine (6)
Glycine (6)
Aspartame (6)
Alpha-ketoglutarate (6)
Guanine (6)
Malonic acid (6)
Adenine (6)
Sucrose (6)
Inosine (6)
2'-deoxyadenosine (5)
N-acetylhistidine (5)
Tryptophan (5)
Proline (5)
Malate (5)
Glutamate (5)
Fumarate (5)
Cysteine (5)
Adenine (5)
Methionine (5)

First Public Date

2014 (7)
2017 (5)
2025 (4)
2024 (4)
2021 (4)
2013 (4)
2026 (3)
2023 (2)
2022 (1)
2019 (1)
2015 (1)

Classification

bacteria (3)
viruses (2)
protozoa (1)

Study type

Transcription profiling by array (4140)
RNA-seq of coding RNA (364)
Unknown experiment type (156)
ChIP-chip by tiling array (156)
Transcription profiling by RT-PCR (85)
ChIP-seq (85)
RNA-seq of non coding RNA (70)
Other (56)
Comparative genomic hybridization by array (54)
Methylation profiling by array (43)
RNA-seq of coding RNA from single cells (43)
Transcription profiling by tiling array (24)
MicroRNA profiling by array (21)
ChIP-chip by array (18)
RNA-seq of total RNA (15)
Methylation profiling by high throughput sequencing (10)
Transcription profiling by SAGE (8)
Genotyping by array (8)
Animal - One-color microarray (5)
Animal - High-throughput sequencing (5)
RNAi profiling by array (5)
Cell line - High-throughput sequencing (4)
DNA-seq (4)
Proteomic profiling by array (4)
MicroRNA profiling by high throughput sequencing (3)
One-color microarray (2)
Cell line - One-color microarray (2)
High-throughput sequencing (2)
MNase-seq (1)
RNA-seq of non coding RNA from single cells (1)

Release Date

2010 (1034)
2013 (700)
2012 (686)
2011 (663)
2014 (601)
2015 (585)
2008 (278)
2016 (266)
2009 (247)
2007 (151)
2025 (117)
2022 (110)
2021 (106)
2023 (87)
2006 (85)
2024 (81)
2019 (81)
2018 (75)
2005 (72)
2017 (64)
2020 (58)
2026 (28)
2004 (13)
2003 (3)
2002 (2)
2000 (2)
2001 (1)

Lab affiliation

State Key Laboratory of Genetic Engineering, Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai 200438, China (5)
State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai 200438, China (3)
NREL (2)
Max Planck Institute for Terrestrial Microbiology Karl-von-Frisch Str. 10 35043 Marburg Germany (2)
KTH Royal Institute of Technology: Stockholm, Stockholm, Sweden School of Engineering Sciences in Chemistry, Biotechnology and Health (1)
State Key Laboratory of Genetic Engineering, Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai 200438, P. R. China (1)
Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China (1)
1. Department of Clinical Genetics, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands 2. Department of Pediatrics, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands 3. Center for Lysosomal and Metabolic Diseases, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands (1)
Institute for Cell Engineering, Sidney Kimmel Comprehensive Cancer Center, Department of Biological Chemistry, McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, USA (1)
SCB Group International Centre for Genetic Engineering and Biotechnology, New Delhi India (1)
State Key Laboratory of Genetic Engineering, School of Life Science, Fudan University, Shanghai, China (1)
ValgepeaLab, Institute of Bioengineering, University of Tartu (1)
Vascular Program, Institute for Cell Engineering, McKusick-Nathans Institute for Genetic Medicine, and Departments of Medicine, Biological Chemistry, Oncology, Pediatrics, and Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. (1)
State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai,China (1)
State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, 200438, China. (1)
State Key Laboratory of Genetic Engineering, Department of Biochemistry, School of Life Sciences, Fudan University (1)
College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China. (1)
TUM School of Natural Sciences, Department Biosciences, Chair of Organic Chemistry II, Center for Functional Protein Assemblies (CPA), Technical University Munich (TUM), Ernst-Otto-Fischer Str. 8, Garching, 85748, Germany (1)
ERA Chair in Gas Fermentation Technologies, Institute of Technology, University of Tartu, Tartu, Estonia (1)
State Key Laboratory of Genetic Engineering & Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200438, China (1)
Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanology, Shenzhen University, Shenzhen, Guangdong, P. R. China (1)
International Centre for Genetic Engineering and Biotechnology Aruna Asaf Ali Marg 110 067 New Delhi, India (1)
Department of Biomedical Engineering, University of Wisconsin-Madison (1)
Broad Institute (1)
Chemistry and Biomolecular Sciences, Faculty of Science and Engineering, Macquarie University (1)
Aix-Marseille Université, CEA, CNRS, Institute of Biosciences and Biotechnologies of Aix-Marseille, UMR 7265, CEA Cadarache, Saint-Paul-lez Durance F-13108, France (1)
Professor of Developmental Biology Director Institute of Biodynamics and Biocomplexity (1)
The Key Laboratory of Resistance Genetic Engineering and Coldland Biodiversity Conservation, College of Life Sciences, Agriculture and Forestry (1)
Institute of pharmacology and structural biology, CNRS, Toulouse, France (1)
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Stomatology, Department of Oral & Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi’ an, PR China. (1)

Previous page
1 / 634
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 634
Next page

Sort by:

Relevance

Page size

Multitrait engineering of Hassawi red rice for sustainable cultivation

Sustainable agriculture requires locally adapted varieties that produce nutritious food with limited agricultural inputs. Genome engineering represents a viable approach to develop cultivars that fulfill these criteria. For example, the red Hassawi rice, a native landrace of Saudi Arabia, tolerates ...

2023-12-14 | MTBLS864 | MetaboLights

Nutritional quality and genetic differences of five amaranth cultivars revealed by metabolome profiling and whole-genome sequencing (Leaf assays)

BACKGROUND: Amaranth (Amaranthus spp.) has high nutritional quality, with edible grain and leaves, and many agronomic advantages, making it a promising part of the solution for global food insecurity. However, we lack comprehensive metabolomic and genome sequence data fo...

2025-02-25 | MTBLS3498 | MetaboLights

Nutritional quality and genetic differences of five amaranth cultivars revealed by metabolome profiling and whole-genome sequencing (Seed assays)

2025-02-25 | MTBLS815 | MetaboLights

Ferritin aggregation: A neotype and universal engager for CAR T cell avidity engineering against diverse refractory leukemias

Introduction: Primary liver cancer remains the third leading cause of global cancer-related mortality, with hepatocellular carcinoma (HCC) constituting the predominant histological subtype. The development of malignant ascites in advanced HCC patients signifies metastatic progression and portends...

2025-12-24 | MTBLS13569 | MetaboLights

Hierarchical regulation in a KRAS pathway-dependent transcriptional network revealed by a reverse-engineering approach

This SuperSeries is composed of the following subset Series: GSE38584: Hierarchical regulation in a KRAS pathway-dependent transcriptional network revealed by a reverse-engineering approach (7TF and control) GSE38585: Hierarchical regulation in a KRAS pathway-dependent transcriptional network reveal...

ORGANISM(S): Rattus norvegicus

2012-07-31 | E-GEOD-38614 | biostudies-arrayexpress

Reverse engineering gene networks: integrating genetic perturbations with dynamical modeling.

Not available

S-EPMC156306 | biostudies-literature

Hierarchical regulation in a KRAS-dependent transcriptional network revealed by a reverse-engineering approach

Mutations in RAS proteins occur in 30% of human tumours and have a high relevance in tumor progression. Despite the importance of the underlying genetic network that governs the effects of oncogenic RAS, it is still poorly understood. We developed and applied a reverse-engineering approach in order ...

ORGANISM(S): Rattus norvegicus

2011-03-01 | E-GEOD-24668 | biostudies-arrayexpress

Reverse engineering of industrial pharmaceutical-producing actinomycete strains

Abstract: Transcript levels in production cultures of wildtype and classically improved strains of the actinomycete bacteria Saccharopolyspora erythraea and Streptomyces fradiae were monitored using microarrays of the sequenced actinomycete S. coelicolor. Sac. erythraea and S. fradiae synthesize the...

ORGANISM(S): Streptomyces coelicolor

2006-03-08 | E-GEOD-4395 | biostudies-arrayexpress

Reverse engineering molecular hypergraphs.

Not available

S-EPMC4051496 | biostudies-literature

Engineering SARS-CoV-2 using a reverse genetic system.

Not available

S-EPMC8168523 | biostudies-literature

Previous page
1 / 634
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 634
Next page

Sort by:

Relevance

Page size

6335 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

CHEBI ID

Metabolite Name

First Public Date

Classification

Study type

Release Date

Lab affiliation

Tags

OmicsDI is part of the ELIXIR infrastructure

Tweets